Molecular and Cellular Approaches to the Control of Proliferation and Differentiation
This book covers the progress made in recent years in our understanding of the relationship between the control of cell growth and differentiation by the combined application of molecular biology, biochemistry and cell biology. It is intended for cell, molecular and developmental biologists, geneticists and oncologists.
- Hardback | 426 pages
- 01 Dec 1991
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
- references, index
Table of contents
Part 1 Regulation of cell proliferation: growth factors - their role in the control of cell proliferation, N.E. Olashaw et al; nuclear proto-oncogenes and growth regulation, B. Calabretta et al; the control of mitotic division, P.N. Rao; cell cycle and cell growth control, K.J. Soprano and S.C. Cosenza; regulation of gene expression by serum growth factors, G.T. Williams et al. Part 2 Cellular, biochemical and molecular parameters of in vitro model systems in which modifications in cell-growth control are functionally related to the onset of differentiation: gene expression during development of the osteoblast phenotype - an integrated relationship of cell growth to diffentiation, J.B. Lian et al; growth and differentiation of myelomonocyctic cells, B.L. Kreider and G. Rovera; erythroleukemia cells, V.M. Richon et al; growth and differentiation in melanocytes, A. Richmond. Part 3 Exploring mechanisms of control: molecular mechanisms that mediate a functional relationship between proliferation and differentiation, G.S. Stein et al; the nuclear matrix - structure and involvement in gene expression, J.A. Nickerson and S. Penman; histone modifications associated with mitotic chromosome condensation, J.P. Th'ng et al.