Molecular and Cell Biology of Pain: Volume 131

Molecular and Cell Biology of Pain: Volume 131

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Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world-wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute and chronic pain. The book will cover a wide array of topics from gene polymorphisms to voltage-gated ion channels moving from cellular biology to whole animal physiology.
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Product details

  • Hardback | 648 pages
  • 152 x 229 x 35.56mm | 1,180g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128013893
  • 9780128013892

Table of contents

An Introduction to Pain Pathways and Pain "Targets"
Vaskar Das
Peripheral Scaffolding and Signaling Pathways in Inflammatory Pain
Nathaniel A. Jeske
Contribution of Mechanosensitive Ion Channels to Somatosensation
Reza Sharif-Naeini
Sensory TRP Channels: The Key Transducers of Nociception and Pain
Aaron D. Mickle, Andrew J. Shepherd and Durga P. Mohapatra
The Contribution of Mitochondria to Sensory Processing and Pain
Sarah J. L. Flatters
Regulation of Gene Expression and Pain States by Epigenetic Mechanisms
Sandrine M. Geranton and Keri K. Tochiki
Translation Control of Chronic Pain
Ohannes K. Melemedjian and Arkady Khoutorsky
MicroRNA Biology and Pain
Marguerite K. McDonald and Seena K. Ajit
Role of Extracellular Damage-Associated Molecular Pattern Molecules (DAMPS) as Mediators of Persisitent Pain
Jungo Kato and Camilla I. Svensson
mGluRs Head to Toe in Pain
Benedict J. Kolber
Non-neuronal Central Mechanisms of Pain: Glia and Immune Response
E. Alfonso Romero-Sandoval and Sarah Sweitzer
Synaptic Inhibition and Disinhibition in the Spinal Dorsal Horn
Steven A. Prescott
Dendritic Spine Dysgenesis in Neuropathic Pain
Andrew Michael Tan
Commonalities between Pain and Memory Mechanisms and their Meaning for Understanding Chronic Pain
Theodore J. Price and Kufreobong E. Inyang
Dietary Influence on Pain via the Immune System
Stacie K. Totsch, Megan E. Waite and Robert E. Sorge
Chemotherapy-Induced Peripheral Neuropathy
Jill C. Fehrenbacher
Stress and Chronic Pelvic Pain
Angela N. Pierce and Julie A. Christianson
Meningeal Afferent Signaling and the Pathophysiology of Migraine
Carolina Burgos-Vega, Jamie Moy and Greg Dussor
Chronic Pain Syndromes, Mechanisms, and Current Treatments
Justin Sirianni, Mohab Ibrahim and Amol Patwardhan
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