The Molecular Biology of Arrestins: Volume 118
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The Molecular Biology of Arrestins: Volume 118

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Description

This special volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of arrestins, with contributions from leaders in the field. Arrestins have emerged as central players in the regulation of many facets of G protein-coupled receptor signaling. This volume covers a variety of topics with reviews written by experts in the field.
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Product details

  • Hardback | 536 pages
  • 154.94 x 231.14 x 30.48mm | 839.14g
  • Academic Press Inc
  • San Diego, United States
  • English
  • New
  • 0123944406
  • 9780123944405
  • 2,159,219

Table of contents

Part I: Perspective - The Duality of Arrestin Function

1. Arrestins Come of Age: A Personal Historical Perspective

Part II: The Molecular Biology of Arrestins




2. True Arrestins and Arrestin-Fold Proteins: A Structure-Based Appraisal




3. Structural Determinants of Arrestin Functions




4. Arrestins: Role in the Desensitization, Sequestration and Vesicular Trafficking of G Protein-Coupled Receptors




5. Arrestins as Regulators of Kinases and Phosphatases




6. ss-Arrestins: Modulators of Small GTPase Activation and Function




7. Arrestins and Protein Ubiquitination




8. Arrestins in Actin Reorganization and Cell Migration

Part III: The Physiological Roles of Arrestins




9. The Role of Arrestins in Development




10. The Role of Arrestins in Visual and Disease Processes of the Eye




11. b-Arrestins in the Central Nervous System




12. Arrestins in the Cardiovascular System




13. Arrestins in Bone




14. b-Arrestins in the Immune System




15. The Role of b-Arrestins in Cancer




16. Arrestins in Metabolic Regulation

Part IV: The Future - The Potential for Arrestin-based Therapeutics




17. Systems Analysis of Arrestin Pathway Functions




18. Arrestin Pathways as Drug Targets
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Review quote

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal
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