Microbial Synthetic Biology: Volume 40

Microbial Synthetic Biology: Volume 40

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The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.

Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.

This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue.
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Product details

  • Hardback | 240 pages
  • 192 x 236 x 20mm | 639.99g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0124170293
  • 9780124170292

About Colin R. Harwood

Colin Harwwod is a professor at Newcastle University
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Table of contents

Computational Intelligence in the Design of Synthetic Microbial Genetic Systems
Jennifer S. Hallinan
Constraints in the Design of the Synthetic Bacterial Chassis
Antoine Danchin and Agnieszka Sekowska
Social Dimensions of Microbial Synthetic Biology
Jane Calvert and Emma Frow
Bacillus Subtilis: Model Gram-positive Synthetic Biology Chassis
Colin R. Harwood, Suzanne Pohl, Wendy Smith and Anil Wipat
Engineering Microbial Biosensors
Lisa Goers, Nicolas Kylilis, Marios Tomazou, Ke Yan Wen, Paul Freemont and Karen Polizzi
Noise and Stochasticity in Gene Expression - A Pathogenic Fate determinant
Mikkel Girke Jorgensen, Renske van Raaphorst and Jan-Willem Veening
Platforms for Genetic Design Automation
Chris J. Myers
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