Metabolism at a Glance

Metabolism at a Glance

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Metabolism at a Glance is a complete review course of metabolism in health and disease and offers a unique approach to the study of this difficult discipline. Metabolism is a complicated subject involving complex molecules and interrelated pathways. These metabolic pathways are usually taught separately with the result that the student develops a detailed but compartmentalised approach to metabolism and frequently fails to see the overall picture and its physiological significance. Using the at a Glance format, the book takes the student through a complete course in intermediary metabolism in an integrated manner. The same chart is repeated throughout the book with the individual pathway under study highlighted. The book is an ideal text for introductory biochemistry courses and has established itself as an enormously popular book amongst lecturers and students alike. This third edition is fully updated and includes five new chapters to mirror those topics currently taught at undergraduate level: 1. Metabolic Channelling 2. Glucose homeostasis and Reye's Disease 3. Pentose phosphate pathway and the prodcution of NADPH 4. Tryptophan metabolism in health and disease 5.
Tyrosine metabolism in health and disease
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Product details

  • Paperback | 128 pages
  • 286 x 342 x 10mm | 798.32g
  • Blackwell Publishing Ltd
  • Oxford, United Kingdom
  • English
  • Revised
  • 3rd Revised edition
  • w. 400 figs.
  • 1405107162
  • 9781405107167
  • 163,161

Back cover copy

"Metabolism at a Glance" is a complete review course of metabolism in health and disease, offering a unique approach to the study of this difficult discipline. Throughout the book, metabolism is presented in an integrated manner. This provides the reader with an overview of separate inter-related pathways as well as 'the big picture' for a greater understanding of the whole subject. Using the classic 'at a glance' format of double-page spreads, the book successfully explains complicated metabolic processes by highlighting the core features in detailed maps whilst the text provides further explanation. The third edition of this bestseller is fully updated and includes six new chapters to mirror those topics currently taught at undergraduate level. New chapters cover metabolic channeling, tryptophan metabolism, tyrosine metabolism in health and disease, and Reye's syndrome. The chapters on glycolysis and the pentose phosphate pathway have been extended. The rapid progress in understanding of the intracellular mechanisms of insulin action in relation to diabetes has necessitated substantial revision and extension of these chapters." " "Metabolism at a Glance" will be an essential resource for students on medical, biochemistry, veterinary, sports science and nutrition courses requiring a knowledge of intermediary metabolism. Those who need an authoritative yet concise guide to metabolism, such as examination candidates, biomedical scientists, and clinicians specializing in diabetes as well as inborn errors of metabolism, will find this book invaluable. The book is designed to fit into the reading time as well as the budget of students and trainees and has established itself as an enormously popular book amongst students and lecturers alike.
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Table of contents

Foreword. Preface. 1 Introduction to Metabolic Pathways. 2 Biosynthesis of ATP, part I. 3 Biosynthesis of ATP, part II. 4 The oxidation of cytosolic NADH + H+. 5 Metabolism of glucose to give energy. 6 Metabolism of one molecule of glucose to form 38 molecules of ATP. 7 Metabolism of glucose to glycogen. 8 Anaerobic metabolism of glucose and glycogen to yield energy as ATP. 9 2,3 Bisphosphoglycerate and the red blood cell. 10 Metabolism of glucose to fat (triacylglycerol). 11 Metabolism of glucose to fatty acids and triacylglycerol. 12 The pentose phosphate pathway and the production of NADPH. 13 The pyruvate/malate cycle and the production of NADPH. 14 Mammals cannot synthesis glucose from fatty acids. 15 Metabolism of triacylglycerol to provide energy as ATP. 16 Glycogen metabolism part I. 17 Glycogen metabolism part II. 18 Glycogen metabolism part III: regulation of glycogen breakdown. 19 Glycogen metabolism part IV : regulation of glycogen biosynthesis. 20 Regulation of glycolysis. 21 Glycolysis and the pentose phosphate pathway in the liver in the fed state. 22 Glycolysis in skeletal muscle; biochemistry of sport and excerise. 23 Regulation of gluconeogenesis. 24 Regulation of the Krebs cycle. 25 Regulation of fatty acid oxidation part I. 26 Regulation of fatty acid oxidation part II. 27 The ketone bodies. 28 Ketone body utilisation. 29 Beta-Oxidation of unsaturated fatty acids. 30 Peroxisomal Beta-oxidation. 31 Elongation and desaturation of fatty acids. 32 Cholestrerol, bile acids and the steroid hormones. 33 The ornithine cycle for the production of urea. 34 Metabolic Channelling. 35 Biosynthesis of the non-essential amino acids. 36 Catabolism of amino acids. 37 Catabolism of amino acids. 38 Metabolism of amino acids to glucose in starvation and during the period immediately after re-feeding. 39 Metabolism of protein to fat. 40 Disorders of amino acid metabolism. 41 Tyrosine metabolism in health and disease. 42 Tyrosine metabolism. 43 Amino acid metabolism, folate metabolism and the 1-carbon pool part I. 44 Amino acid metabolism, folate metabolism and the 1-carbon pool part II. 45 Porphyrin metabolism, heam and the bile pigments. 46 Metabolism of ethanol. 47 Sorbitol, galactitol, glucaronate and xylitol. 48 Fructose metabolism. 49 Glucose homeostasis: Reye's syndrome. 50 Diabetes I: insulin-stimulated glycogen synthesis. 51 Diabetes II: metabolic changes in Type I diabetes. 52 Diabetes III: Type I diabetes, type II diabetes, MODY and pancreatic Beta-cell metabolism. 53 Diabetes IV: type II diabetes and insulin resistance in muscle. 54 Diabetes V: type II diabetes and insulin resistance in adipose tissue. 55 Diabetes VI: type II diabetes and insulin resistance in liver. Index.
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Review Text

On the first edition:§§"...a highly comprehensive set of notes and pathway mapsconcentrated exclusively on metabolism. If you are after an easygoing metabolism book for revision or as a good reference guide,this would be the ideal choice, as it is not too daunting to readand had plenty of well-organised pathway maps to keep you busy.This is especially useful for first year medics as part of theirfoundation study revision"§§ Leech y Gelen, University of Wales College ofMedicine"§§"The book is easy to follow as the salient features of eachmetabolic pathway are highlighted on a detailed background map.This aided the introduction of the metabolic concepts in a verywell-integrated fashion. The chapters on the more medical aspectswill appeal especially to medical students as they correlate neatlythe basic biochemical principles with the development of somemetabolic diseases such as glycogen storage diseases."§§ Biochemistry and Molecular Biology Education §
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Review quote

On the first edition: "...a highly comprehensive set of notes and pathway maps concentrated exclusively on metabolism. If you are after an easy going metabolism book for revision or as a good reference guide, this would be the ideal choice, as it is not too daunting to read and had plenty of well-organised pathway maps to keep you busy. This is especially useful for first year medics as part of their foundation study revision" Leech y Gelen, University of Wales College of Medicine" "The book is easy to follow as the salient features of each metabolic pathway are highlighted on a detailed background map. This aided the introduction of the metabolic concepts in a very well-integrated fashion. The chapters on the more medical aspects will appeal especially to medical students as they correlate neatly the basic biochemical principles with the development of some metabolic diseases such as glycogen storage diseases." Biochemistry and Molecular Biology Education
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Rating details

25 ratings
4.48 out of 5 stars
5 60% (15)
4 28% (7)
3 12% (3)
2 0% (0)
1 0% (0)
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