Medical and Surgical Report of the Presbyterian Hospital in the City of New York Volume 8

Medical and Surgical Report of the Presbyterian Hospital in the City of New York Volume 8

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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1908 edition. Excerpt: ...Eighty-eight per cent. of my cases have shown definite changes in these bodies. In thirty per cent. of cases, some or all of the islands of Langerhans exhibited hyaline degeneration with consequent partial destruction. Lesions of the islands of Langerhans have usually been associated with chronic interacinar pancreatitis and arteriosclerosis. In twelve cases insular changes have occurred in an otherwise normal pancreas. Are the lesions of the islands of Langerhans sufficiently severe to produce loss of function? In most instances, there can be little doubt that hyaline degeneration and sclerosis have an injurious effect. Even where there is only a moderate thickening of the insular capillaries, the change is doubtless sufficient to interfere with the proper nutrition of the cells. (2). Are lesions of the islands of Langerhans secondary to diabetes? There is no evidence in support of this view. The variety of lesions of these structures, associated with diabetes, affords evidence that they are not the result of the same cause. As a rule sclerosis of islands of Langerhans is associated with a chronic interacinar pancreatitis; diabetes with a destructive lesion of the pancreas, is comparable to diabetes following removal of the gland in lower animals. In cases where the parenchyma is normal, sclerosis of the islands of Langerhans is limited to the capillary wall and appears to be part of a general arteriosclerosis. Is the cause of pancreatic diabetes to be found in lesions of the parenchyma, in lesions of the islands of Langerhans, or in both combined? Chronic interacinar pancreatitis alone does not answer the question, for both structures are implicated. On the other hand, with forms of chronic inflammation due, for example, to duct obstruction, more

Product details

  • Paperback | 120 pages
  • 189 x 246 x 6mm | 227g
  • Miami Fl, United States
  • English
  • black & white illustrations
  • 1236650352
  • 9781236650351