The Medical Standard Volume 45, No. 11

The Medical Standard Volume 45, No. 11

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1922 edition. Excerpt: ...stains (Nissl's) are necessary to determine the entire picture, especially as regards the anterior horn cells. Lapinsky himself found no changes with the older staining methods, but he found them with the newer ones. The author also opposes the newer views of Dejerine that the changes in the anterior horn cells are the result of axonal degeneration and closes his discussion by stating that there are no good grounds for blaming these changes in tabes on a tabetic neuritis. Lapinsky is the leading exponent of the theory that the change is primarily in the anterior horn cells. With Nissl's stain he found in serial sections these changes in the cells: the cells were swollen, the Nissl bodies in part were grouped around the nucleus. The nuclei were likewise swollen and altered in their shape and sometimes peripherally placed. Various peripheral nerves and muscles showed degenerative changes which had their origin in these cells. Clinically, there were various differences from the neuritis of Dejerine. The localization of the atrophy does not indicate a distribution of the nerve trunks, since some muscles were only in part atrophied, and in the same muscles normal bundles were near the involved ones. There was no symmetry in the affected muscles. The author concludes that muscle atrophy in tabes occurs under these conditions: (1) Accompanying disease. (2) As a result of the general weakness and anesthesia of the muscles toward the end of the disease. (3) As a result of the peripheral neuritis hrought out, not through the poison of tabes, but through other injurious processes. (4) As a result of the localization of the specific trouble of tabes in the nerve roots and anterior horn cell, whereby the motor impulses are more or less impaired....show more

Product details

  • Paperback | 38 pages
  • 189 x 246 x 2mm | 86g
  • Rarebooksclub.com
  • United States
  • English
  • black & white illustrations
  • 1236949617
  • 9781236949615