Excerpt from The Medical Fortnightly, Vol. 46: A Progressive Biweekly Magazine for the General Practitioner; August 25, 1914
One of the fairly constant symptoms of typhoid fever is meteorism. The badly mixed semi-ﬂuid mass in the small intestine becomes the seat for organic chemical changes; and in the splitting up of com pounds, and the new arrangements of atoms in molecules. Gas is developed. There is a record in eastern Montana of a country doctor who inserted a trocar and canula into a typhoid fever patient's abdo men with the idea of tapping the gaseous contents of the small intestine. The gas proved to be principally sulphuretted hy drogen and was disposed of by combustion.
High temperature, meteorism. Diarrhea, and general sepsis are the objective symp toms of the third stage of typhoid fever. To treat the disease at any stage it is nec essary to remove the cause. Hypodermic injection of typho-bacterin is scientific treatment. But it must be well considered that the typhoid bacillus operates from headquarters in the small intestine. Toxin manufactured in that locality is absorbed through the gut into blood vessels and lymphatics, and this is the reason it is the exception rather than the rule to find living bacilli in the blood stream and interior tis sues.
Bacterin injections act indirectly because it must reach the stronghold of the enemy indirectly; in other words, it must make the round trip through the circulation and risk elimination through the bowel in order to attack, in situ, the exciting cause of the disease. An army is incapable of doing its best fighting at the close of a day's march; similarly it might be predicated that bacterin which has passed through the circulation has been shorn of its strength if not indeed totally disorganized.
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