Mechanisms and Concepts in Toxicology

Mechanisms and Concepts in Toxicology

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Description

Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.
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Product details

  • Hardback | 254 pages
  • 170 x 244 x 20mm | 580.61g
  • London, United Kingdom
  • English
  • references, index
  • 0748404139
  • 9780748404131

Table of contents

Scope of Toxicology


Stages in the Induction of Toxicity


Kinetics and End-points


Acute and Chronic Intoxication


Delivery of Intoxicant: Decrease in Delivery to the Target


Delivery of Intoxicant: Bioactivation and Increase in Delivery to the Target


Initiating Reactions with Targets


Biological Consequences of Initiating Reactions with Targets


Exposure, Dose and Chemical Structure, Response and Activity, and Thresholds


Selective Toxicity, Animal Experimentation and In Vitro Methods


Biomonitoring


Epidemiology


Environmental and Ecotoxicology


Reflections, Research and Risk
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