A Means to an End : The Biological Basis of Aging and Death
This work covers ageing from a fundamental cell biological perspective. The evolution and developmental genetics of senescence are explained clearly. All the various theories of ageing - the Hayflick limit and telomeric shortening as a possible biological clock, the impacts of somatic mutations, oxidative stress, accumulation of waste materials in cells with age - are explained and critically assessed. The author presents vivid case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan.
- Hardback | 251 pages
- 152.4 x 233.68 x 27.94mm | 521.63g
- 22 Apr 1999
- Oxford University Press Inc
- New York, United States
- 21 line drawings
About William R. Clark
Professor Emeritus of Immunology at UCLA and an internationally recognized authority on cellular immune reactions, William R. Clark is the author of The New Healers: Molecular Medicine in the Twenty-First Century, Sex and the Origins of Death, and At War Within: The Double Edged Sword of Immunity, all published by OUP.