Magnetic Resonance Imaging

Magnetic Resonance Imaging : Methods and Biologic Applications

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Leading experts in the use of MRI explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications. To illustrate its capability to reveal exquisite anatomical detail, the authors discuss MRI applications to developmental biology, mouse phenotyping, and fiber architecture. MRI can also provide information about organ and tissue function based on endogenous cantrast mechanisms. Examples of brain, kidney, and cardiac function are included, as well as applications to neuro and tumor pathophysiology. In addition, the volume demonstrates the use of exogenous contrast material in functional assessment of the lung, noninvasive evaluation of tissue pH, the imaging of metabolic activity or gene expression that occur on a molecular level, and cellular labeling using superparamagnetic iron oxide contrast agents.
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Product details

  • Hardback | 447 pages
  • 154.94 x 231.14 x 25.4mm | 861.82g
  • Totowa, NJ, United States
  • English
  • 2006 ed.
  • XV, 447 p.
  • 1588293971
  • 9781588293978

Back cover copy

Even as magnetic resonance imaging (MRI) has matured into an invaluable diagnostic tool, it has also become a key experimental tool in biological research, where it demonstrates special sensitivity to a plethora of physiological factors, as well as a capacity for use all the way from cellular suspensions to in vivo human studies. In Magnetic Resonance Imaging: Methods and Biologic Applications, leading experts in the use of MRI from both academia and industry explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications. To illustrate its capability to reveal exquisite anatomical detail, the authors discuss MRI applications to developmental biology, mouse phenotyping, and fiber architecture. MRI can also provide information about organ and tissue function based on endogenous contrast mechanisms. Examples of brain, kidney, and cardiac function are included, as well as applications to neuro- and tumor pathophysiology. In addition, the volume demonstrates the use of exogenous contrast material in functional assessment of the lung, noninvasive evaluation of tissue pH, the imaging of metabolic activity or gene expression that occur on a molecular level, and cellular labeling using superparamagnetic iron oxide contrast agents.
Cutting-edge and user-friendly, Magnetic Resonance Imaging: Methods and Biologic Applications illuminates for biological scientists the basic principles of MRI and shows how it can be used successfully to solve important biological problems.
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Table of contents

I. Introduction



Introduction to Magnetic Resonance Imaging and Spectroscopy

Pippa Storey



Magnetic Resonance Microscopy: Concepts, Challenges, and State-of-the-Art

Barjor Gimi



II. Anatomy



Magnetic Resonance Imaging of Embryonic and Fetal Development in Model Systems

Eric T. Ahrens, Mangala Srinivas, Saverio Capuano, Hyagriv N. Simhan, and Gerald P. Schatten



Mouse Morphological Phenotyping With Magnetic Resonance Imaging

X. Josette Chen



Magnetic Resonance Microscopy of Mouse Brain Development

Susumu Mori, Jiangyang Zhang, and Jeff W. M. Bulte



III. Physiology



Quantitative Perfusion Imaging Using Arterial Spin Labeling

Donald S. Williams



Physiology of Functional Magnetic Resonance Imaging: Energetics and Function

Ikuhiro Kida and Fahmeed Hyder



Functional Magnetic Resonance Imaging of the Kidney

Pottumarthi V. Prasad



Cardiac Magnetic Resonance Spectroscopy: A Window for Studying Physiology

Michael Horn



IV. Pathophysiology



Application of Magnetic Resonance Imaging to Study Pathophysiology in Brain Disease Models

Rick M. Dijkhuizen



Magnetic Resonance Imaging of Tumor Physiology

Arvind P. Pathak



Magnetic Resonance Imaging in Preclinical Drug Development

Matthew D. Silva and Sudeep Chandra



V. Novel Contrast Agents and Mechanisms



Hyperpolarized Gas and Oxygen-Enhanced Magnetic Resonance Imaging

Vu M. Mai



Tissue pH Measurement by Magnetic Resonance Spectroscopy and Imaging

Natarajan Raghunand



Biological Applications of Manganese-Enhanced Magnetic Resonance Imaging

Robia G. Pautler



Targeted Magnetic Resonance Imaging Contrast Agents

Shelton D. Caruthers, Patrick M. Winter, Samuel A. Wickline, and Gregory M. Lanza



Design and Characterization of Magnetic Resonance Imaging Gene Reporters

Angelique Louie



Intracellular Endosomal Magnetic Labeling of Cells

Jeff W. M. Bulte



Index
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Review Text

From the reviews:

"Magnetic Resonance Imaging: Methods and Biologic Applications offers something of interest for MRI novices as well as more experience practitioners. The language is clear and easy to read, and the diagrams ... are very helpful." (AuntMinnie.com, February, 2006)

"This book is one of a large series of books on Methods in Molecular Medicine, edited by John M. Walker with 28 contributors ... . The authors are distinguished, primary basic scientists in basic science departments or departments of cardiology or radiology. ... I believe this book would be valuable for departments that are about to use or are using MRI as a research tool ... and as an addition to department libraries dealing with this technique." (Joseph P. Whalen, Clinical Imaging, Vol. 30, 2006)
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Review quote

From the reviews:



"Magnetic Resonance Imaging: Methods and Biologic Applications offers something of interest for MRI novices as well as more experience practitioners. The language is clear and easy to read, and the diagrams ... are very helpful." (AuntMinnie.com, February, 2006)

"This book is one of a large series of books on Methods in Molecular Medicine, edited by John M. Walker with 28 contributors ... . The authors are distinguished, primary basic scientists in basic science departments or departments of cardiology or radiology. ... I believe this book would be valuable for departments that are about to use or are using MRI as a research tool ... and as an addition to department libraries dealing with this technique." (Joseph P. Whalen, Clinical Imaging, Vol. 30, 2006)
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About Pottumarthi V. Prasad

Prasad - in den USA als Paul Duffy geboren - ist ein moderner Repräsentant des Advaita. In Indien traf er auf seinen Lehrer H.W.L. Poonja und beschäftigte sich intensiv mit den Weisheiten von Ramana Maharshi. Er hält zahlreiche Satsangs und Retreats ab und veröffentlichte seine spirituellen Anleitungen auch auf Video und CD.
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