Lipoxygenases and Their Products
Lipoxygenases are enzymes involved in the conversion of arichidonic acid to leukotrienes and lipoxins. These serve a variety of important functions and have been implicated in a wide range of human diseases. This book looks at the structure, pharmacology, and cellular mechanisms of action of lipoxygenases and their metabolic products.
- Hardback | 278 pages
- 01 May 1991
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
Table of contents
Pharmacology and pathophysiology of 5-lipoxygenase products, E.F.Smith III et al; regulation and structure of human leukocyte 5-lipoxygenase, C.Rouzer; the structure and regulation of 5-lipoxygenase in rat basophilic leukemia cells, A.Wong and S.T.Crooke; arachidonate 5-lipoxygenase of porcine leukocytes studied using its monoclonal antibodies, T.Yoshimoto et al; enzymatic studies on purified 5-lipoxygenase, W.DeWolf, Jr; potential and therapeutic value of development of novel 5-lipoxygenase inhibitors, A.W.Ford-Hutchinson; the physiological role of 15-lipoxygenase, J.Y.Vanderhoek; receptor subtypes and antagonists for mammalian 5-lipoxygenase products, S.Mong; third generation peptidoleukotriene receptor antagonists, M.A.Lewis et al; lipoxins - bioactive lipoxygenase interaction products, S.E.Dahlen and C.Serhan.