Ion Channels as Therapeutic Targets, Part B: Volume 104

Ion Channels as Therapeutic Targets, Part B: Volume 104

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Description

This volume is the second part of the thematic on Ion Channels as Therapeutic Targets.

The popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists, brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
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Product details

  • Hardback | 466 pages
  • 152 x 229 x 27.94mm | 880g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128048263
  • 9780128048269

Table of contents

Role of Hemichannels in CNS Inflammation and the Inflammasome Pathway
Yuri Kim, Joanne O. Davidson, Katherine C. Gunn, Anthony R. Phillips, Colin R. Green and Alistair J. Gunn
P2X7 Receptors as a Therapeutic Target
Elena De Marchi, Elisa Orioli, Diego Dal Ben and Elena Adinolfi
Polymodal Transient Receptor Potential Vanilloid Type 1 (TRPV1) Nocisensor: Structure, Modulators, and Therapeutic Applications
Minghua Cui, Vijayakumar Gosu, Shaherin Basith, Sunhye Hong and Sun Choi
TRPM8 ion Channels as Potential Cancer Biomarker and Target in Pancreatic Cancer
Nelson S. Yee
Ion Channels In The Eye: Involvement In Ocular Pathologies
Jonathan P Giblin, Nuria Comes, Olaf Strauss and Xavier Gasull
Calcium-Activated Potassium Channels: Potential Target for Cardiovascular Diseases
De-Li Dong, Yun-Long Bai and Ben-Zhi Cai
The Modulation of Potassium Channels in the Smooth Muscle as a Therapeutic Strategy for Disorders of the Gastrointestinal Tract
Diego Curro
Targeting the Channel Activity of Viroporins
Janet To, Wahyu Surya and Jaume Torres
Contribution of Automated Technologies to Ion Channel Drug Discovery
Arturo Picones, Arlet Loza-Huerta, Pedro Segura-Chama and Cesar O. Lara Figueroa
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About Rossen Donev

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2010 Dr. Donev was appointed Lecturer in Swansea University. Currently he is Director of Biomed Consult Ltd, UK. His major research interests include signalling pathways involved in neuropsychiatric disorders and tumour escape from the immune system, and development of therapeutic strategies for treatment. He has published more than 50 research papers, has chaired scientific meetings in Molecular Medicine and given plenary talks at Attention Deficit/Hyperactivity Disorder meetings. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals.
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