Introduction to Biocatalysis Using Enzymes and Microorganisms

Introduction to Biocatalysis Using Enzymes and Microorganisms

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This is an introductory text intended to give the non-specialist a comprehensive insight into the science of biotransformations. The book traces the history of biotransformations, clearly spells out the pros and cons of conducting enzyme-mediated versus whole-cell bioconversions, and gives a variety of examples wherein the bio-reaction is a key element in a reaction sequence leading from cheap starting materials to valuable end-products (such as pharmaceuticals and agrochemicals, fragrances and flavours). Biotransformations involving the hydrolysis of esters, amides and nitriles, the synthesis of esters and amides, reduction and oxidation reactions and carbon-carbon bond-forming systems are discussed. The book finishes with a discussion of some industrially important large-scale bioconversions.
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Product details

  • Electronic book text
  • Cambridge University Press (Virtual Publishing)
  • Cambridge, United Kingdom
  • 35 b/w illus. 19 tables
  • 1139243098
  • 9781139243094

Table of contents

Preface; 1. An historical introduction to biocatalysis using enzymes and microorganisms; 2. The inter-relationship between enzymes and cells with particular reference to whole-cell biotransformations using bacteria and fungi; 3. Useful intermediates and end-products obtained from whole-cell/enzyme catalysed hydrolysis and esterification reactions; 4. Useful intermediates and end-products obtained from biocatalysed oxidation and reduction reactions; 5. Useful intermediates and end-products obtained from biocatalysed carbon-carbon, carbon-oxygen, carbon-nitrogen, and carbon-chalcogen bond-forming reactions; 6. The application of biocatalysis to the manufacture of fine chemicals; Index.
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Review quote

' ... the book is well presented and has few errors. It is a readable and affordable introduction for those new to this area, particularly synthetic chemists, and would also be useful for an advanced undergraduate or a postgraduate course in the subject.' Chemistry in Britain
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