Introduction to Biocatalysis Using Enzymes and Microorganisms
This is an introductory text intended to give the non-specialist a comprehensive insight into the science of biotransformations. The book traces the history of biotransformations, clearly spells out the pros and cons of conducting enzyme-mediated versus whole-cell bioconversions, and gives a variety of examples wherein the bio-reaction is a key element in a reaction sequence leading from cheap starting materials to valuable end-products (such as pharmaceuticals and agrochemicals, fragrances and flavours). Biotransformations involving the hydrolysis of esters, amides and nitriles, the synthesis of esters and amides, reduction and oxidation reactions and carbon-carbon bond-forming systems are discussed. The book finishes with a discussion of some industrially important large-scale bioconversions.
- Electronic book text
- 11 May 2012
- CAMBRIDGE UNIVERSITY PRESS
- Cambridge University Press (Virtual Publishing)
- Cambridge, United Kingdom
- 35 b/w illus. 19 tables
Table of contents
Preface; 1. An historical introduction to biocatalysis using enzymes and microorganisms; 2. The inter-relationship between enzymes and cells with particular reference to whole-cell biotransformations using bacteria and fungi; 3. Useful intermediates and end-products obtained from whole-cell/enzyme catalysed hydrolysis and esterification reactions; 4. Useful intermediates and end-products obtained from biocatalysed oxidation and reduction reactions; 5. Useful intermediates and end-products obtained from biocatalysed carbon-carbon, carbon-oxygen, carbon-nitrogen, and carbon-chalcogen bond-forming reactions; 6. The application of biocatalysis to the manufacture of fine chemicals; Index.
' ... the book is well presented and has few errors. It is a readable and affordable introduction for those new to this area, particularly synthetic chemists, and would also be useful for an advanced undergraduate or a postgraduate course in the subject.' Chemistry in Britain