Immunopharmacology of Free Radical Species

Immunopharmacology of Free Radical Species

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This text covers free radicals. Free radicals have been implemented in many different human disease states, which suggests that they may not have a pivotal aetiological role in any, but sre involved in the perpetuation of disease. In recent years, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems maintaining normal cell function. It is the perturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing from this new knowledge. The "Handbook of Immunopharmacology" series follows three main themes, each represented by volumes on individual component topics.
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Product details

  • Hardback | 277 pages
  • 203 x 267 x 23mm | 822g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0121035204
  • 9780121035204

About David Blake

Edited by Clive Page, David Blake, and Paul G. Winyard
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Table of contents

Methods for the detection and measurement of reactive radical species "in vivo" and "in vitro", M. Grootveld and C.J. Rhodes; lipid peroxidation and cardiovascular disease, V.M. Darley-Usmar et al; free radicals and antioxidants in atherosclerosis, C. Rice-Evans; oxidant stress and the heart - modulation of ion transport mechanisms during ischaemia and reperfusion, M.J. Shattock and P.S. Haddock; free radicals in central nervous system diseases, J.A. Clemens and J.A. Patetta; renal transplantation and ischaemia-reperfusion injury, C.J. Green; a vascular basis for free radical involvement in inflammatory joint disease, M.L. Kus et al; reactive oxygen species in skin inflammation, C.J. Morris et al; free radicals, inflammation and eye diseases, M. Goss-Sampson; free radicals in gastrointestinal and hepatic disease, M.J. Jackson; free radicals, oxidative stress and diabetes mellitus, A.J. Sinclair and J. Lunec; DNA damage by free radicals - carcinogenic implications, O.I. Aruoma and B. Halliwell; free radicals in lung inflammation and environmental exposure to pollutants, M. Yeadon; free radicals and liver injury, K.H. Cheeseman.
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