The Immune Response

The Immune Response : Basic and Clinical Principles

4.6 (5 ratings by Goodreads)
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Description

The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences.
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Product details

  • Hardback | 1216 pages
  • 224 x 286 x 56mm | 3,238.68g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Approx. 450 illustrations (250 in full color)
  • 0120884518
  • 9780120884513
  • 1,551,976

Table of contents

BASIC IMMUNOLOGY
Perspective on Immunity
Introduction to the Immune Response
Cells and Tissues of the Immune Response
Innate Immunity
B Cell Receptor Structure and Effector Function
Antigen-Antibody Interaction
Exploiting Antigen-Antibody Interaction
The Immunoglobulin Genes
The Humoral Response: B Cell Development and Activation
The Major Histocompatibility Complex
Antigen Processing and Presentation
T Cell Receptor: Structure of its Proteins and Genes
T Cell Development
T Cell Activation
T cell differentiation and effector function
Immune Tolerance in the Periphery
Cytokines and their Receptors
Bridging Innate and Specific Immunity: NK, gd T and NKT cells
Complement
Mucosal and Cutaneous Immunity
Comparative Immunology
CLINICAL IMMUNOLOGY
Immunity to Pathogens
Vaccines and Clinical Immunization
Primary Immunodeficiencies
HIV and Acquired Immunodeficiency Syndrome
Tumor Immunology
Transplantation
Allergy and Hypersensitivity
Autoimmune Disease
Glossary
Appendices
Index
Abbreviations
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Review quote

"...sets a high standard of excellence in the immunologic literature."
- Robert S. Schwartz, M.D. for THE NEW ENGLAND JOURNAL OF MEDICINE

"This is a valuable book for any veteran immunologist or student of immunology..."
- Sam Mehr, MBBS, BMedSci, The Children's Hospital at Westmead for Doody's: 3 Star Review

"...useful to serious students entering the field or to those in the field who want a well-written update across the breadth of immunology"
- Andrew Saxon for CLINICAL IMMUNOLOGY (Jan 2006)

"The Immune Response is a well-written, well-organized, learner-centered text that is suitable for undergraduates, medical and graduate students, and more advanced learners of immunology."
- James T. Li for JAMA (March 2006)


"...a well-written, well-organized, learner-centered text that is suitable for undergraduates, medical and graduate students, and more advanced learners of immunology."
- James T. Li for JAMA (March 2006)

"...very erudite and quite complete and accurate in its coverage."
-Peter Ward, University of Michigan Health Systems, Department of Pathology, USA (2004)

"...reads very well, and should be of great interest to those wanting to get a start in understanding Immunology."
-Juan-Carlos Zuniga-Pflucker, Sunnybrook & Women's College Heath Sciences Centre, USA (2004)

"The illustrations are terrific."
- Douglas Green, La Jolla Institute of Allergy and Immunology, USA (2004)

"...straight forward style...crystal clear definitions of complex immunological concepts."
-Gillian Wu, Faculty of Pure and Applied Science, York University, Canada (2004)

"One of the things I especially like is the use of the "Introducing..." and "More about...." sections..."
-Douglas Green, La Jolla Institute of Allergy and Immunology, USA

"...very timely, reads very well...should be of great interest to those wanting to get a start in understanding Immunology."
- Juan-Carlos Zuniga-Pflucker, Sunnybrook & Women's College Health Sciences Centre, USA

"...very erudite and quite complete and accurate in its coverage..."
-Peter Ward, University of Michigan Health Systems, Department of Pathology, USA

"...straight forward style...crystal clear definitions of complex immunological concepts."
-Gillian Wu, Faculty of Pure and Applied Science, York University, Canada
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About Tak W. Mak

Tak W. Mak is the Director of the Campbell Family Institute for Breast Cancer Research in the Princess Margaret Hospital, Toronto, Canada, and a University Professor in the Departments of Medical Biophysics and Immunology, University of Toronto. He was trained at the University of Wisconsin in Madison, the University of Alberta, and the Ontario Cancer Institute. He gained worldwide prominence in 1984 as the leader of the team that first cloned the genes of the human T cell antigen receptor. His group went on to create a series of genetically altered mice that have proved critical to understanding intracellular programs governing the development and function of the immune system, and to dissecting signal transduction cascades in various cell survival and apoptotic pathways. His current research remains centered on mechanisms of immune recognition/regulation, malignant cell survival/death, inflammation in autoimmunity and cancer, and metabolic adaptation in tumor cells. Dr. Mak has published over 700 papers and holds many patents. He has been granted honorary doctoral degrees from universities in North America and Europe, is an Officer of the Orders of Canada and Ontario, and has been elected a Foreign Associate of the National Academy of Sciences (U.S.), a Fellow of the Royal Society of London (U.K.), and a Fellow of the AACR Academy. Dr. Mak has won international recognition as the recipient of the Emil von Behring Prize, the King Faisal International Prize for Medicine, the Gairdner Foundation International Award, the Sloan Prize of the General Motors Cancer Foundation, the Novartis Prize in Immunology, the Robert Noble Prize, the Killam Prize, the Stacie Prize, the McLaughlin Medal, and the Paul Ehrlich and Ludwig Darmstaedter Prize. Mary E. Saunders holds the position of Scientific Editor for the Campbell Family Institute for Breast Cancer Research, Toronto, Canada. She completed her B.Sc. degree in Genetics at the University of Guelph, Ontario, and received her Ph.D. in Medical Biophysics at the University of Toronto. Dr. Saunders works with Dr. Mak and members of his laboratory on the writing and editing of scientific papers for peer-reviewed journals as well as on various grant applications and book projects. She takes pride and pleasure in producing concise, clear, highly readable text and making complex scientific processes readily understandable. Maya R. Chaddah graduated with a double major in Human Biology and Spanish, followed by an M.Sc. in Immunology at the University of Toronto. In 1996, Ms. Chaddah started a business focused on the writing and editing of scientific and medical publications. Her expertise has grown to include scientific and medical illustration, and she continues to produce a variety of communications for diverse audiences in the public and private sectors.
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Rating details

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4.6 out of 5 stars
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3 20% (1)
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