Hypertension and Hormone Mechanisms
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Hypertension and Hormone Mechanisms

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Description

This book reviews novel developments in the endocrinology of hypertension with emphasis on new discovery during the past five years and perspectives on the future. It is written by authors who have spearheaded recent advances. With a focus on new developments in hormones and autacoids related to hypertension, the book provides a resource that will lead to new, active research in the fundamental mechanisms of hypertension.show more

Product details

  • Hardback | 378 pages
  • 177.8 x 256.54 x 27.94mm | 952.54g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • 2007 ed.
  • 16 Tables, black and white; XII, 378 p.
  • 1588294080
  • 9781588294081

Back cover copy

Hypertension, a major risk factor for cardiovascular disease and stroke, is present in approximately one-quarter of the adult population of Western societies. Advances in the study and treatment of this condition are captured in this exceptionally important book. In Hypertension and Hormonal Mechanisms, distinguished panels of leading experts discuss new developments in hormones/autacoids related to hypertension. During the past decade, truly remarkable advances have been made in the identification of new components of the renin-angiotensin system. This book also provides the most up to date advancements in topics such as the importance of diabetes and obesity in hypertension and the new role of calcitonsin gene-related peptide (CGRP) in hypertension. Hypertension and Hormonal Mechanisms, written by the world's experts in this field, aims to open new doors leading researchers closer to understanding the etiology and pathogenesis of primary (essential) hypertension, and to stimulate active research in the fundamental mechanisms of hypertension so that new therapies, and even prevention, can be realized in the not-too-distant future.show more

Review quote

From the reviews: "This is a comprehensive overview of pathophysiology of hypertension. ... The book is targeted at both scientists and clinicians with the goal of providing a basic foundation to better understand mechanisms involved in hypertension as well as stimulate active research to better understand the fundamental mechanisms of the disease. ... useful and very thorough summary of the hormonal mechanisms of hypertension. It is an excellent resource for clinicians and scientists involved in the treatment of hypertension as well as those engaging in basic science research." (Irena Duka, Doody's Review Service, December, 2007) "The book provides a unique review of the latest developments and discoveries in the endocrinology of hypertension . ... it also provides the reader with the most recent discoveries brought about by basic clinical science research. ... This book will be of utmost interest to clinicians and basic scientists ... as well as to specialists such as endocrinologists, cardiologists, and nephrologists. I strongly recommend that it should be available in all medical school libraries." (Edgar V. Lerma, JAMA, May, 2008) "As edited by Dr. Carey, a well-recognized investigator in this field, leading experts provide very comprehensive discussions of the effect of the different hormonal systems on progression of cardiovascular disease. ... this book provides a nice combination of both basic science and clinical considerations of hormonal causes of hypertension and vascular disease. ... Overall, the book will serve as a valuable resource for scientists and clinicians interested in the underlying mechanisms of hypertension and vascular disease." (David A. Calhoun, Endocrinology, Vol. 33 (4), April, 2008)show more

Table of contents

Hypertension and Hormonal Mechanisms Chapter Outline (A) New Developments in the Renin-Angiotensin System 1. The Intrarenal Renal-Angiotensin System Minolfa C. Prieto-Carrasquero, Hiroyuki Kobori and L. Gabriel Navar Tulane University 2. Cardiac and Vascular Renin-Angiotensin Systems Rajesh Kumar, Kenneth M. Baker and Jing Pan Texas A & M University Health System 3. Regulation of Cardiovascular Control Mechanisms by Angiotensin (1-7) and Angiotensin Converting Enzyme-2 Carlos M. Ferrario, David B. Averill, K. Bridget Brosnihan, Mark C. Chappell, Debra I. Diz, Patriciai E. Gallagher, Liomar A.A. Neves and E. Ann Tallant Wake Forest University 4. Angiotensin IV and the AT4 Receptor T. A. Jenkins, F.A.O. Mendelsohn, A.L. Albiston and S.Y. Chai Howard Florey Institute of Experimental Physiology and Medicine, Melbourne 5. AT2 Receptors in Blood Pressure Regulation Robert M. Carey and Helmy M. Siragy University of Virginia Health System 6. Angiotensin II and Inflammation Rhian M. Touyz and Ernesto L. Schiffrin Clinical Research Institute of Montreal 7. Aldosterone and Vascular Damage Hilton V. Joffe, Gordon H. Williams and Gail K. Adler Harvard Medical School (B) The Sympatho-Adrenal System in Hypertension 8. Neurogenic Human Hypertension David Robertson, Andre Diedrich and Italo Biaggioni Vanderbilt University 9. Calcitonin Gene-Related Peptide and Hypertension Donald J. DiPette and Scott C. Supowit Texas A& M University 10. The Renal Dopaminergic System in Hypertension Pedro A. Jose, Robert M. Carey and Robin A. Felder Georgetown University and the University of Virginia Health System (C) Metabolic Disorders and Hypertension 11. The Insulin Resistance Syndrome and Hypertension James R. Sowers University of Missouri 12. Fatty Acids and Hypertension Brent M. Egan Medical University of South Carolina 13. Goal-Oriented Hypertension Management in Diabetic and Non-Diabetic Patients Gregory M. Singer, John F. Setaro and Henry R. Black Rush Presbyterian - St. Luke's Medical Cente (D) Endothelial Hormones and Autacoids and Hypertension 14. Nitric Oxide and Hypertension David L. Mattson and Allen W. Cowley Medical College of Wisconsin 15. Role of Endothelin 1 in Hypertension Ernesto L. Schiffrin Clinical Research Institute of Montreal 16. The Kallekrein/Kinin System and Hypertension Julie Chao and Lee Chao Medical University of South Carolina (E) Other Hormonal Systems and Hypertension 17. Natriuretic Peptides and Hypertension Kailesh N. Pandey Tulane University 18. Sex Steroids and Hypertension Suzanne Oparil and Andrew Miller University of Alabama Birmingham 19. The Lipoxygenase System in the Vasculature and Hypertension Naftali Stern and Michael Tuck Tel Aviv University and UCLA School of Medicineshow more

Review Text

From the reviews: "This is a comprehensive overview of pathophysiology of hypertension. ... The book is targeted at both scientists and clinicians with the goal of providing a basic foundation to better understand mechanisms involved in hypertension as well as stimulate active research to better understand the fundamental mechanisms of the disease. ... useful and very thorough summary of the hormonal mechanisms of hypertension. It is an excellent resource for clinicians and scientists involved in the treatment of hypertension as well as those engaging in basic science research." (Irena Duka, Doody's Review Service, December, 2007) "The book provides a unique review of the latest developments and discoveries in the endocrinology of hypertension . ... it also provides the reader with the most recent discoveries brought about by basic clinical science research. ... This book will be of utmost interest to clinicians and basic scientists ... as well as to specialists such as endocrinologists, cardiologists, and nephrologists. I strongly recommend that it should be available in all medical school libraries." (Edgar V. Lerma, JAMA, May, 2008) "As edited by Dr. Carey, a well-recognized investigator in this field, leading experts provide very comprehensive discussions of the effect of the different hormonal systems on progression of cardiovascular disease. ... this book provides a nice combination of both basic science and clinical considerations of hormonal causes of hypertension and vascular disease. ... Overall, the book will serve as a valuable resource for scientists and clinicians interested in the underlying mechanisms of hypertension and vascular disease." (David A. Calhoun, Endocrinology, Vol. 33 (4), April, 2008)show more