Hematopoietic Stem Cell Niche: Volume 1

Hematopoietic Stem Cell Niche: Volume 1

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Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice.show more

Product details

  • Paperback | 186 pages
  • 152 x 229 x 10.16mm | 320g
  • Elsevier Science Publishing Co Inc
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128113758
  • 9780128113752

Table of contents

Stroma Cell Niche Regulation During HSC Development G. Stik, P. Charbord and C. Durand The Evolvement of Hematopoietic Stem Cell NichesB.O. Zhou, L. Li and M. Zhao The Role of the CNS in the Regulation of HSCsA. Garcia-Garcia and S. Mendez-FerrerImaging the Haematopoietic Stem Cell NicheD. Duarte and C.L. CelsoMechanisms of Hematopoietic Stem and Progenitor Cells Bone Marrow Homing and MobilizationA. Kumari, T. Lapidot, K. Golan, E. Khatib-Massalha and O. KolletAlterations of HSC Niche in Myeloid MalignanciesL. Han and M. KonoplevaTargeting the Bone Marrow Niche in Hematological MalignanciesD. Verma and D.S. Krauseshow more

About Dominique Bonnet

Dominique Bonnet is a Senior Group Leader at the Francis Crick Institute. She is also Professor at the University College of London and a Senior Lecturer at the Institute of Child Health.show more