Hans Krebs

Hans Krebs : The Formation of a Scientific Life 1900-1933

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This is the first volume of the definitive biography of Hans Krebs, one of the world's foremost biochemists. It begins with the early work of Krebs in Germany, where, working with Otto Warburg, he discovered the urea cycle in 1932. This early achievement, coupled with the discovery of the citric acid cycle, are viewed as the foundations upon which the modern structure of intermediary metabolism is built. During the writing of this fascinating history, the author not only had access to a complete set of Krebs' key laboratory notebooks, but to the man himself through five years of insightful interviews. Holmes captures Krebs' activities at a level of intimacy that reveals scientific creativity at work. The story weaves together the investigative pathway with the professional and personal life of the investigator. The Krebs biography is certain to fascinate biochemists and historians of science alike.
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Product details

  • Hardback | 512 pages
  • 164.1 x 241.3 x 35.3mm | 911.74g
  • Oxford, United Kingdom
  • English
  • New
  • halftones, line drawings
  • 0195070720
  • 9780195070729

Table of contents

Intermediary metabolism in the first third of the twentieth century; Boyhood in Hildesheim; Outward movement; Clinical years; The research apprentice; Initiative and dependence; Moves toward autonomy; Freiburg: The foundation of a career; The ornithine effect; The formation of urea; The rewards of success; The brief life of a Freiburg school of metabolism; Reflections on the formation of a scientific life.
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Review quote

'This is not only a study of Krebs's research, it is also a comprehensive biography of Krebs's personal as well as scientific life ... These two volumes represent an extraordinary achievement, as a biography of a man, living in a time of turmoil and upheaval, who emerged as a great scientists. The story of both the man and the science is full and rewarding. Among studies of biochemists, I know of nothing in the least comparable with Holmes's achievement here, in
its depth and breadth.'
John T. Edsall, Harvard University, Nature, Vol. 366, December 1993 `By any standards, Hans Krebs: the formation of a scientific life is a staggering achievement. In it, Holmes has shown himself the master of biochemical minutiae and of German cultural and intellectual life in the first third of this century. His scene-setting chapter on the history of intermediary metabolism before Krebs is a tour-de-force ... a major biochemist, a volume which should find an appreciative audience among scientists
and historians alike.'
Times Higher Education Supplement
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