Handbook of Toxicologic Pathology

Handbook of Toxicologic Pathology

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This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.
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Product details

  • Hardback | 1127 pages
  • 228.1 x 287.3 x 51.6mm | 3,135.16g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 450 illustrations and half-tones, 93 tables, references, index
  • 012330220X
  • 9780123302205

Table of contents

Toxicologic pathology - an introduction, R.W. Leader; the pathologist in toxicologic testing and evaluation, D.C. Dodd; evaluation of altered morphology, T.J. Bucci; quantitative techniques for morphological evaluation, M.J. Evans, et al; biochemical basis of toxicity, E.H. Jeffrey; biochemical mechanisms of toxic cell injury, M.E. Kyle and J.L. Farber; chemical carcinogenesis, R.R. Maronpot; limitations of toxicologic pathology, Z. Ruben and C.G. Rousseaux; regulatory aspects and potential pitfalls of toxicologic pathology, P.K. Hildebrandt; risk assessment, J.F. Van Gelder; skin and oral mucosa, A.J.P. Klein-Zanto, et al; gastrointestinal tract, T.A. Bertram; pancreas, D.S. Longnecker and G.L. Wilson; hepatobiliary system, J.A. Popp and R.C. Cattley; urinary system, C.L. Alden and C.H. Frith; blood and bone marrow, R.D. Irons; immune system, H.J. Schuurman, et al; skeletal system, J.C. Woodard and W.S.S. Jee; cardiovascular and skeletal muscular systems, J.F. Van Vleet, et al; nervous system, A. Koestner and S. Norton; endocrine system, C.C. Capen, et al; respiratory system, W.M. Haschek; male reproductive system, D.M. Creasy and P.M.D. Foster; female reproductive system, Y.D. Yuan; the fetus, C.G. Rousseaux and P.M. Blakley; radiation and heat, S.A. Benjamin, et al.
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