Handbook of Proteolytic Enzymes
This text and CD-ROM details proteolytic enzymes by name and history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features. It is divided into five sections: peptidases of serine, cysteine, aspartic, metallo, and unknown catalytic mechanism. The CD-ROM features a fully-searchable text, specialized scissile bond search, zoomable colour 3D structures, amino acid sequence information and internal and external hyperlinking.
- Mixed media product | 1758 pages
- 163.1 x 243.3 x 14.7mm | 385.56g
- 01 Oct 1998
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
"Rated 5 Stars!..... This book is highly recommended for anyone with an interest in proteolytic enzymes and is probably the only truly comprehensive handbook of this type available. It represents a massive effort by the editors and contributors and will likely be the primary source of such information in the future." - Doody's Publishing Reviews
Table of contents
(Abbreviated Contents Including Section Headings:) Serine Peptidases. Serine Peptidases and Their Clans. Family S1 of Trypsin (Clan SA). Tissue Kallikrein and Its Relatives. Other Families of Clan SA. Clan SB Containing the Subtilisin Family. Clan SC Containing Peptidases with the Alpha/Beta Hydrolase Fold. Clan SE Containing Serine-Type D-Ala-D-Ala Peptidases. Clan SF Containing Peptidases with a Ser/Lys Catalytic Dyad. Clan SH Containing Herpesvirus Assemblins. Clan TA Containing N-Terminal Nucleophile Peptidases. Other Families of Serine Peptidases. Unsequenced Serine Peptidases. Cysteine Peptidases. Cysteine Peptidases and Their Clans. Clan CA Containing Papain and Its Relatives. Clan CC Containing Viral 'Papain Like' Cysteine Endopeptidases. Clan CB Containing the Nodavirus Coat Protein. Other Families of Aspartic Endopeptidases. Metallopeptidases. Metallopeptidases and Their Clans. Clan MA Containing Thermolysin and Its Relatives. Family M1 of Membrane Alanyl Aminopeptidase. Other Families of Clan MA. Family M3 of Thimet Oligopeptidase. Clan MB Containing 'Metzincins' (Clan MB). Family M10 of Interstitial Collagenase (Clan MB). Family M12 of Astacin (Clan MB). Introduction to the Reprolysins (Family M12). Clan MC Containing the Metallocarboxypeptidases. Clan MD Containing Zinc D-Ala-D-Ala-Carboxypeptidase. Clan ME Containing Pitrilysin and Its Relatives. Clan MF Containing Co-Catalytic Leucyl Amino-Peptidases. Clan MG Containing the Methionyl Aminopeptidase Family. Clan MH Containing Varied Co-Catalytic Metallopeptidases. Other Families of Metallopeptidases. Metallopeptidases of Unknown Sequence. Unclassified Peptidases. Peptidases of Unknown Catalytic Type. Subject Index.
About Alan John Barrett
Alan J. Barrett, Residence: Cambridge, U.K., Affiliation: The Babraham Institute - Neil D. Rawlings, Residence: Cambridge, U.K., Affiliation: The Babraham Institute - J. Fred Woessner, Jr., Residence: Miami, Florida, Affiliation: University of Miami School of Medicine, Florida.