Handbook of Physiology: The Gastrointestinal System Section 6

Handbook of Physiology: The Gastrointestinal System Section 6

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For the first time in the history of the "Handbook of Physiology", a volume is devoted to neural and endocrine biology of the gut. This book is an up-to-date reference work that emphasizes the pharmacology, physiology, and cellular and molecular biology of hormonal and neural peptides of the gut. The early chapters deal with fundamental topics such as post-translational processing of gut peptides, immunocytochemistry of endocrine cells and enteric neurons, tissue distribution of peptides, comparative neuroendocrinology, trophic actions and the physiological significance of hormonal, paracrine and neural peptides. Several subsequent chapters deal with receptors of pancreatic acinar cells, gastric parietal cells, intestinal epithelial cells, liver cells and smooth muscle cells. The remaining 14 chapters are devoted to individual peptides and describe their distribution, pharmacology, and physiological and cellular functions.
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Product details

  • Hardback | 790 pages
  • 215 x 280 x 50.8mm | 2,514g
  • New York, United States
  • English
  • Subsequent
  • black and white photographs, figures and tables
  • 0195208161
  • 9780195208160

Table of contents

I. SALIVARY: J.W. Putney: Calcium signaling system in salivary glands; Electrophysiology of salivary and pancreatic acinar cells; T.N. Spearman, & F.R. Butcher: Cellular regulation of amylase secretion by the parotid gland; D.O. Quissell: Salivary mucin secretion; L.S. Cutler: Functional differentiation of salivary glands; R.S. Cameron, P. Arvan, & J.D. Castle: Secretory membranes and the exocrine storage compartment; II. PANCREAS: J.A. Williams, D.B. Burnham, & S.R. Hootman: Cellular regulation of pancreatic secretion; I. Schulz: Signaling transduction in hormone- and neurotransmitter-induced enzyme secretion from the exocrine pancreas; S.R. Rothman: Regulation of digestive reactions by the pancreas; G.A. Scheele, & H.F. Kern: Cellular compartmentation and protein processing in the exocrine pancreas; G.A. Scheele, & Horst F. Kern: Selective regulation of gene expression in the exocrine pancreas; R.M. Case, & B.E. Argent: Pancreatic secretion of electrolytes and water; C.D. Logsdon: Long-term regulation of pancreatic function studied in vitro; A. Chang, & J.D. Jamieson: Structural and secretory polarity in the pancreatic acinar cell; S.J. Konturek: Inhibition of gastric acid secretion; B.I. Hirschowitz: Neural and hormonal control of gastric secretion; J.R. Demarest, & T.E. Machen: Electrophysiology of gastric ion transport; S.J. Hersey: Cellular basis of pepsinogen secretion; J.G. Forte, & A. Soll: Cell biology of hydrochloric acid secretion; G. Sachs, J. Kaunitz, J. Mendlein, & B. Wallmark: Biochemistry of gastric acid secretion: H+ - K+ - ATPase; B.H. Hirst: The gastric mucosal barrier; G. Flemstrom, & A. Garner: Secretion of bicarbonate by gastric and duodenal mucosa; A. Smolka: Immunological probes of gastrointestinal secretion; C-C. Tseng, & L.R. Johnson: Functional development of stomach; A. Allen: Gastrointestinal mucus; C.S. Chew: Intracellular activation events for parietal cell hydrochloric acid; III. HEPATOBILIARY: A.F. Hofmann: The secretion of bile: an overview; A.F. Hofmann: Enterohepatic circulation of bile acis; D.J. Cabral: Physical chemistry of bile; A.L. Jones, & S.J. Burwen: Pathways and functions of biliary potein secretion; K.K.F. Meijer: Transport and metabolism in the hepatobiliary system; R.W. Van Dyke, J.R. Lake, & B.F. Scharschmidt: Cellular mechanisms of hepatic fluid and electrolyte transport; E.L. Forker: Hepatic transport of organic solutes; N.F. LaRusso: Hepatocyte lysosomes in intracellular digestion and biliary secretion
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