Handbook of Nuclear Medicine and Molecular Imaging for Physicists
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Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures, Volume I

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Description

This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine. It provides a thorough treatment on the cutting-edge technologies being used within the field, in addition to touching upon the history of their use, their development, and looking ahead to future prospects.


This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine.








The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine







Edited by a leader in the field, with contributions from a team of experienced medical physicists







Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history
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Product details

  • Hardback | 640 pages
  • 210 x 280mm
  • CRC Press
  • London, United Kingdom
  • English
  • 224 Line drawings, black and white; 155 Halftones, black and white; 57 Tables, black and white; 379 Illustrations, black and white
  • 1138593265
  • 9781138593268

Table of contents

Contents


Preface...............................................................................................................................................................................ix


Contributors......................................................................................................................................................................xi


Editor Bio....................................................................................................................................................................... xiii


Chapter 1 The History of Nuclear Medicine.................................................................................................................1


Bo- Anders Joensson


Chapter 2 Basic Atomic and Nuclear Physics.............................................................................................................15


Gudrun Alm Carlsson and Michael Ljungberg


Chapter 3 Basics of Radiation Interactions in Matter.................................................................................................39


Michael Ljungberg


Chapter 4 Radionuclide Production............................................................................................................................69


Hans Lundqvist


Chapter 5 Radiometry.................................................................................................................................................89


Mats Isaksson


Chapter 6 Scintillation Detectors..............................................................................................................................107


Per Roos


Chapter 7 Semiconductor Detectors.........................................................................................................................129


Per Roos


Chapter 8 Gamma Spectrometry...............................................................................................................................145


Christopher Raaf


Chapter 9 Properties of the Digital Image................................................................................................................175


Katarina Sjoegreen Gleisner


Chapter 10 Image Processing......................................................................................................................................197


Johan Gustafsson


Chapter 11 Machine Learning....................................................................................................................................221


Karl Astroem


Chapter 12 Image File Structures in Nuclear Medicine..............................................................................................237


Charles Herbst


Chapter 13 The Scintillation Camera..........................................................................................................................251


Jonathan Gear


Chapter 14 Collimators for Gamma Ray Imaging......................................................................................................265


Roel van Holen


Chapter 15 Image Acquisition Protocols....................................................................................................................279


Jonathan Gear


Chapter 16 Single Photon Emission Computed Tomography (SPECT) and SPECT/ CT Hybrid Imaging................297


Michael Ljungberg and Kjell Erlandsson


Chapter 17 Dedicated Tomographic Single Photon Systems......................................................................................315


Jing Wu and Chi Liu


Chapter 18 PET Systems............................................................................................................................................333


Stefaan Vandenberghe


Chapter 19 Dead- time Effects in Nuclear Medicine Imaging Studies........................................................................343


Carlos Uribe and Anna Celler


Chapter 20 Principles of Iterative Reconstruction for Emission Tomography...........................................................355


Andrew J. Reader


Chapter 21 PET-CT Systems......................................................................................................................................389


Dimitris Visvikis


Chapter 22 Clinical Molecular PET/ MRI Hybrid Imaging........................................................................................397


Bernhard Sattler


Chapter 23 Quality Assurance of Nuclear Medicine Systems....................................................................................427


John Dickson


Chapter 24 Calibration and Traceability.....................................................................................................................455


Brian E. Zimmerman


Chapter 25 Activity Quantification from Planar Images............................................................................................463


Katarina Sjoegreen Gleisner


Chapter 26 Quantification in Emission Tomography..................................................................................................479


Brian F. Hutton, Kjell Erlandsson, and Kris Thielemansii


Chapter 27 Multicentre Studies: Hardware and Software Requirements...................................................................499


Terez Sera, Ronald Boellaard, Andres Kaalep, and Michael Ljungberg


Chapter 28 Preclinical Molecular Imaging Systems...................................................................................................515


Magnus Dahlbom


Chapter 29 Monte Carlo Simulation of Nuclear Medicine Imaging Systems............................................................533


David Sarrut and Michael Ljungberg


Chapter 30 Beta and Alpha Particle Autoradiography................................................................................................563


Anders OErbom, Brian W. Miller and Tom Back


Chapter 31 Principles behind Computed Tomography (CT)......................................................................................589


Mikael Gunnarsson and Kristina Ydstroem


Chapter 32 Principles behind Magnetic Resonance Imaging (MRI)..........................................................................605


Ronnie Wirestam
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About Michael Ljungberg

Michael Ljungberg is a Professor at Medical Radiation Physics, Lund, Lund University, Sweden. He started his


research in the Monte Carlo field in 1983 through a project involving a simulation of whole-body counters but later


changed the focus to more general applications in nuclear medicine imaging and Single Photon Emission Computed


Tomography (SPECT). As a parallel to his development of the Monte Carlo code SIMIND, he started working in 1985


with quantitative SPECT and problems related to attenuation and scatter. After earning his PhD in 1990, he received


a research assistant position that allowed him to continue developing SIMIND for quantitative SPECT applications


and established successful collaborations with international research groups. At this time, the SIMIND program also


became used worldwide. Dr. Ljungberg became an associate professor in 1994 and in 2005, after working clinically as a


nuclear medicine medical physicist, received a full professorship in the Science Faculty at Lund University. He became


head of the Department of Medical Radiation Physics in 2013 and a full professor in the Medical Faculty in 2015.


Besides the development of SIMIND to include a new camera system with CZT detectors, his research includes


an extensive project in oncological nuclear medicine and, with colleagues, he developed dosimetry methods based on


quantitative SPECT, Monte-Carlo absorbed dose calculations, and methods for accurate 3D dose planning for internal


radionuclide therapy. In recent years, his work has focused on implementing Monte-Carlo based image reconstruction


in SIMIND. He is also involved in the undergraduate education of medical physicists and biomedical engineers and is


supervising MSC and PhD students. In 2012, Professor Ljungberg became a member of the European Association of


Nuclear Medicines task group on dosimetry and served in that group for six years. He has published over a hundred


original papers, 18 conference proceedings, 18 books and book chapters and 14 peer- reviewed papers.
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