Handbook of Cannabis and Related Pathologies

Handbook of Cannabis and Related Pathologies : Biology, Pharmacology, Diagnosis, and Treatment

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Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs.

Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug's effects from across scientific disciplines.

This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders.

Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects.
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Product details

  • Hardback | 1170 pages
  • 216 x 276 x 60.96mm | 3,330g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128007567
  • 9780128007563
  • 1,396,542

Table of contents

The Cannabis Plant: Botanical Aspects
The biosynthesis of cannabinoids
Increasing plant concentrations of THC and implications on health related disorders
Age as a Predictor of Cannabis Use
Lifetime cannabis use and cognition in psychosis spectrum disorders
A Profile of Synthetic Cannabinoid Users
Dual disorders in cannabis misuse
Cannabis use and cognitive function
Cannabis, migration and psychosis onset
The global epidemiology and disease burden of cannabis use and dependence
International aspects of cannabis use and misuse - the Australian perspective
International aspects of cannabis use and misuse: Egypt
Cannabis Body Packing - A Caribbean Perspective
Gender differences in cannabis use disorders
The role of age in the onset and further development of cannabis use disorders
Effects of Cannabis Use on Neurocognition in Adolescents and Emerging Adults with Psychiatric Comorbidities
Correlates and consequences of prenatal cannabis exposure (PCE): identifying and characterizing vulnerable maternal populations and determining outcomes for exposed offspring
Cannabis and clubbing: Relevance of cannabis and polydrug use in the clubbing culture today
Cannabis and Sexual Behavior
Friendships and Cannabis Use
Students' knowledge of cannabis
Childhood trauma and cannabis - risk factors in severe mental disorders
Parent's Influence on Their Children's Cannabis Use
Cannabis Users and Premorbid Intellectual Quotient (IQ)
Cannabis and traffic accidents
Drug-related pictures, attentional bias, and cannabis use
Cannabis use and first-episode psychosis patients (FEP)
Cannabis, associative memory, fMRI, and the Implicit Association Test
Stress Response in Cannabis Users and Psychosis
Motivation in Chronic Cannabis Use
Cannabis use and its association to mental illness: a focus on mood and anxiety disorders
Cannabis Use and Well-being
Craving and cannabis: A potential paradox
Delta 9-tetrahydrocannabinol and catalepsy-like immobilization
The interactive nature of cannabis and schizophrenia risk genes
Neuroimaging findings in Adolescent Cannabis use and Early Phase Psychosis
Cannabis smoking in adult schizophrenia: A cognitive and functional magnetic resonance imaging perspective
The long-lasting effects of cannabis use on movement and brain regions that control movement
Assessment of cannabis acute effects on driving skills: laboratory, simulator and on road studies
Chronic cannabis use and axonal fibre connectivity
Microglial activation and cannabis exposure
Cannabis and psychosis: correlation, causality and consequences
Cannabis use and cannabis use disorders in bipolar disorder - causes and consequences
Cannabis use in epilepsy - risks and benefits
Cannabis, cannabinoids and visceral pain.
Cannabis and Post-Operative Analgesia
Chronic cannabis abuse and thyroid function
Cannabis Hyperemesis Syndrome
Cannabis and Cannabinoids and the effects on gastrointestinal function: an overview
Cardiovascular Effects of Cannabis Usage
Cannabis and Stroke
Cannabis Smoking and the Lung
Cannabis and hepatic injury
Cannabis allergy: more than a bad trip
Marijuana and Breastfeeding
Hypocretins/orexins and addiction: role in cannabinoid dependence
Regulatory role of cannabinoids for skin barrier functions and cutaneous inflammation
Cannabinoids and the Cannabinoid Receptors: An Overview
Signalling and Regulation of the Cannabinoid CB1 Receptor
Allosteric modulation of the Cannabinoid CB1 Receptor
The polymorphisms of the CB2 cannabinoid receptor
Chemistry of Cannabinoid Receptor Agonists
The endocannabinoid system as a target for new antiseizure drugs
Pharmacological aspects of anandamide and 2-arachidonoyglycerol as bioactive lipids
Pharmacological aspects of NMDA receptors, mGluR5, and endocannabinoids
Peripheral CB1 receptors and ghrelin in feeding regulation. Pharmacological implications.
Pharmacological aspects of novel antiobesity agents related to cannabinoids
Cannabinoid reward and dependence: Focus on the main psychoactive ingredients of marijuana in preclinical studies
Peroxisome proliferator activated receptors and cannabinoids VRP suggested Peroxisome proliferator activated receptors (PPARs) and cannabinoids
The Protein-Protein interactions of CRIP1a and cannabinoid 1 receptor: the molecular mechanism study through an integrated molecular modeling approach
Synthetic cannabinoids: A summary of selected phenomena with respect to behavioral pharmacology and abuse liability
The role of 5-HT1A receptor and nausea and vomiting relief by cannabidiol (CBD), cannabidiolic acid (CBDA) and cannabigerol (CBG)
Genetic and molecular aspects of addiction with tetrahydrocannabinol
Effects of dlta ï 9-Tetrahydrocannabinol in human breast cancer
Î 9-THC and COX-2 Signaling
Cannabinoids and the addictive effects of nicotine
Cannabinoid Regulation of Intraocular Pressure: Human and Animal Studies, Cellular and Molecular Targets
Ocular Delivery of Tetrahydrocannabinol
The role of g-aminobutyric acid in the interoceptive effects of oral D9-tetrahydrocannabinol in humans
The role of the delta-9-tetrahydrocannabinol in diabetes mellitus
Cannabidiol: An Overview of its Antipsychotic Properties
Cannabidiol for the treatment of epilepsy: an overview of possible mechanisms of action and preclinical and human studies
Cannabidiol and neuroprotection: evidence from preclinical studies
Cannabinoids as Potent Inhibitors of Human CYP1 Enzymes
Nabilone: Pharmacology and Clinical Applications (Suggest: The Synthetic Analogue of delta 9-tetrahydrocannabinol (THC): Nabilone. Pharmacology and Clinical Application)
Synthetic cannabinoids in dementia
Synthetic cannabinoid receptor agonists ("Spice") as new recreational psychoactive substances
Accidents and synthetic cannabinoids in blood of drivers
Cannabis and synthetic cannabinoids for cancer patients: Multiple palliative indications together with promising laboratory anti-neoplastic effects
The Use of Medical Marijuana in the Treatment of Psychiatric Disorders
Beneficial effects of cannabis and related compounds on sleep
Cannabinoids for the treatment of Gilles de la Tourette syndrome
Cannabidiol and multiple sclerosis
Cannabinoids and Effects on Painful Neuropathy
Cannabis for basal ganglia disorders (Parkinson's disease and Huntington's disease)
Medical cannabis for the treatment of Inflammatory Bowel Disease
Cannabidiol for the treatment of drug use disorders
Cannabinoids and the effects on gastrointestinal tract: a focus on motility
Potential medical uses of cannabigerol: a brief overview
The Cannabis Abuse Screening Test (CAST) and applications
Screening of synthetic cannabinoids
On-site Drug testing for Cannabis
Cannabinoids in Oral Fluid: Identification and Interpretation of Analytical Results
Cannabinoids in exhaled breath
Barriers to treatment seeking for cannabis dependence
Pharmacotherapies for cannabis use disorders
Self-Initiated Cannabis Use Cessation in Adolescents and Emerging Adults
Treating cannabis dependent adolescents with family therapy
Cognitive Behavioral Therapy in Cannabis Use Disorder
Cannabis withdrawal symptoms in cannabis and poly drug users
School-based cannabis prevention programs
The CapOpus trial for cannabis use disorders
Treating cannabis use disorders through technology assisted interventions: the telephone and internet
Reducing cannabis use with a real-time intervention using mobile technology
Further information: Cannabis Neuropathology Resources and Recommended Reading

Online Only Chapters:

Tetrahydrocannabinol concentration and genetic characterization of cannabis.
Cannabis Use in Youth Subcultures
Aggressive Behavior and Cannabis Use
COMT genotypes, cannabis use and psychosis: gene-environment interaction evidence from human populations and its methodological concerns
Neuroimaging and genetics of acute and chronic cannabis effects
Grey matter, lateral ventricle volumes and executive functioning in cannabis users with first-episode psychosis
Comorbidity Between Cannabis Use and Attention-Deficit/Hyperactivity Disorder: Potential Moderators
Cannabis and Oral Bones: Deleterious Effects on Periodontitis and Dental Implants
Does cannabis use increase the risk of developing cancer in humans?
Cannabis and the use of amphetamine-like substances
Cannabinoid signaling in glioma cells and therapeutic implications
Cannabidiol as antioxidants
The anxiolytic effects of cannabidiol (CBD).
New Ethological and Morphological Perspectives for the Investigation of Panicolytic-Like Effects of Cannabidiol
Spice Use amongst United States Military Personnel
Cannabis use in fibromyalgia
Short instruments to screen for "problematic" cannabis use in general population surveys: a systematic review
Self-report of cannabis use
CANDIS Program: Modular Treatment of Cannabis Use Disorders
Engaging Cannabis Users in Treatment
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About Victor R. Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.
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