The HDL Handbook

The HDL Handbook : Biological Functions and Clinical Implications

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Description

The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.
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Product details

  • Hardback | 296 pages
  • 152.4 x 231.14 x 17.78mm | 612.35g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Illustrations (some col.)
  • 0123821711
  • 9780123821713

Table of contents

Introduction



Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis
The role of CETP in HDL metabolism
The physiological role of CETP in HDL molecule metabolism
HDL and reverse cholesterol transport: Physiological modulation
Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress
Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL
Apoliopoprotein A-I mutations
The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling
HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease
Sterol efflux by ABCA1 and ABCG1
Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases
Pre?1-HDL: Conversion to and from spherical ?-migrating HDL in human plasma
Determination of circulating native and denaturated HDL concentrations and its clinical implications
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About Tsugikazu Komoda

1969 Graduated Kitasato University School of Medicine 1979 Promoted Assistant Professor of Saitama Medical University 1982 Promoted Assosiate Professor of Saitama Medical Universiy 1983 Co-opereted the intestinal alkaline phosphatase with Professor David H. Alpers, Washington University School of Medicine (St. Louis) 1988 Received a Kodama Memorial Award from Japanese Society of Electrophoresis. 1996 Became Chief Professor of Biochemistry, Saitama Medical University. 2010 Resigned from Saitama Medical University. 2010~ Promoted a Visiting Professor of Toho University School of Medicine Expert Field: alkaline phosphatase, amylase, oxizized HDL
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