Guanfacine

Guanfacine

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Description

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Guanfacine (brand name Tenex, and the extended release Intuniv) is an agonist of the 2A subtype of norepinephrine receptors. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention abilities via modulating post-synaptic 2A receptors in the prefrontal cortex. Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system -2a norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone. Its side-effects are dose dependent, with frequency and severity almost disappearing at doses of 2 mg and less.show more

Product details

  • Paperback | 64 pages
  • 152 x 229 x 4mm | 104g
  • Cel Publishing
  • United States
  • English
  • black & white illustrations
  • 6136767325
  • 9786136767321