Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles

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Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry.
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Product details

  • Paperback | 632 pages
  • 216 x 276mm
  • United States
  • English
  • Reprint
  • 012810158X
  • 9780128101582

Table of contents

1. Green synthetic approaches for biologically relevant heterocycles: An overview 2. Synthesis of bioactive five- and six-membered heterocycles catalyzed by heterogeneous supported metals 3. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes 4. Metal-catalyzed routes for the synthesis of furocoumarins and coumestans 5. Green solvents for eco-friendly synthesis of bioactive heterocyclic compounds 6. Green catalytic synthesis of heterocyclic structures using carbon dioxide and related motifs 7. Synthetic approaches to small and medium size aza-heterocycles in aqueous media 8. Green synthetic approaches for biologically relevant 2-amino-4H-pyrans and 2-amino-4H-pyran-annulated heterocycles in aqueous media 9. Sustainable synthesis of benzimidazoles, quinoxalines and congeners 10. Green and catalytic methods for γ-lactone synthesis 11. Green synthetic approaches for medium ring-sized heterocycles of biological interest 12. Organocatalyzed Biginelli reactions: A greener chemical approach for the synthesis of biologically active 3,4-dihydropyrimidin-2(1H)-ones/-thiones 13. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest 14. Organo hypervalent iodine reagents in the synthesis of bioactive heterocycles 15. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds 16. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles 17. Ionic liquids prompted synthesis of biologically relevant five and six-membered heterocyclic skeletons: An update 18. Heterocycles-based ionic liquid-supported synthesis of small organic molecules 19. Microwave-induced synthesis of heterocycles of medicinal interests 20. Application of microwave irradiation in the synthesis of P-heterocycles 21. Use of ultrasound in the synthesis of heterocycles of medicinal interest
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About Goutam Brahmachari

Professor Dr. Goutam Brahmachari was born at Barala in the district of Murshidabad (West Bengal), India, on April 14, 1969. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher secondary Education (WBCHSE). Then he moved to Visva-Bharati (a central university founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, Prof. Brahmachari completed his masters in 1992 with specialization in organic chemistry and thereafter received his PhD degree in 1997 in chemistry from the same university. He was appointed as assistant professor of organic chemistry in the Department of Chemistry, Visva-Bharati University, in 1998, and became associate professor in 2008. In 2011, he became full professor of organic chemistry in the same faculty. At present, he is responsible for teaching courses in organic chemistry, natural products chemistry, and physical methods in organic chemistry. Several students have received their PhD degree under the supervision of Prof. Brahmachari during this period, and a couple of research fellows are presently working with him both in the fields of natural products and synthetic organic chemistry. He serves as a member of the Indian Association for the Cultivation of Science (IACS) and Indian Science Congress Association (ISCA), Kolkata, and as an Editor-in-Chief, Signpost Open Access Journal of Organic and Biomolecular Chemistry. He also serves as an editorial advisory board member for several journals and is the Who's Who in the World-2015 Listee. He is a recipient of the 3rd Academic Brilliance Award-2015 (Award for Excellence in Research). Prof. Brahmachari's research interests include (i) synthetic organic chemistry with special emphasis on green chemistry; (ii) isolation, structural determination, and/or detailed NMR study of new natural products from medicinal plants; (iii) semi-synthetic studies with natural products; and (iv) evaluation of biological activities and pharmacological potential of natural and synthetic compounds. With more than 16 years of teaching experience, he has produced so far nearly 120 scientific publications including original research papers, review articles, and invited book chapters in edited books in the field of natural products and organic synthesis from internationally reputed presses. Prof. Brahmachari has authored/edited a number of text and major reference books that include Organic Name Reactions: A Unified Approach (Narosa Publishing House, New Delhi; co-published by Alpha Science International, Oxford, 2006), Chemistry of Natural Products: Recent Trends & Developments (Research Signpost, 2006), Organic Chemistry Through Solved Problems (Narosa Publishing House, New Delhi; co-published by Alpha Science International, Oxford, 2007), Natural Products: Chemistry, Biochemistry and Pharmacology (Narosa Publishing House, New Delhi; co-published by Alpha Science International, Oxford, 2009), Handbook of Pharmaceutical Natural Products-2 volume-set (Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2010), Bioactive Natural Products: Opportunities & Challenges in Medicinal Chemistry (World Scientific Publishing Co. Pte. Ltd., Singapore, 2011), Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds (CRC Press, Taylor & Francis group, USA, 2013), Natural Bioactive Molecules: Impacts & Prospects (Narosa Publishing House, New Delhi; co-published by Alpha Science International, Oxford, 2014), Green Synthetic Approaches for Biologically Relevant Heterocycles (Elsevier Inc., USA, 2014), and Bioactive Natural Products-Chemistry & Biology (Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2015). He is regularly consulted as a referee by leading international journals including Elsevier, Royal Society of Chemistry, American Chemical Society, Wiley, Taylor & Francis, Springer, Bentham Science, Indian Chemical Society, Pakistan Chemical Society, Korean Chemical Society, Brazilian Chemical Society, Bulgarian Academy of Sciences, and so on, and also various financial commissions. Prof. Brahmachari enjoys Songs of Rabindranath Tagore and finds interests in Literature as well!
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