Glycosylphosphatidylinositol (GPI) Anchoring of Proteins

Glycosylphosphatidylinositol (GPI) Anchoring of Proteins

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Description

This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins.show more

Product details

  • Hardback | 500 pages
  • 149.86 x 228.6 x 27.94mm | 521.63g
  • Elsevier Science Publishing Co Inc
  • Academic Press Inc
  • San Diego, United States
  • English
  • New.
  • 0123749638
  • 9780123749635

Table of contents

Chapter 1: Overview of GPI biosynthesis, gene list Taroh Kinoshita Chapter 2: GlcNAc transfer reaction, GPI-GnT, Ras signaling David E. Levin Chapter 3: GlcNAc-PI de-N-acetylase Michael A. J. Ferguson Chapter 4: Inositol acylation/deacylation Yoshifumi Jigami Chapter 5: Mannosylation Yusuke Maeda Chapter 6: Phosphoethanolamine transfer Peter Orlean Chapter 7: Transamidase Anant K. Menon Chapter 8: Flipping and pathway topology Anant Menon Chapter 9: Evolutional conservation and Bioinformatics John Samuelson Chapter 10: GPI in apicomplexan and parasites Ralph Schwarz Chapter 11: Chemical synthesis of GPI Ram A. Vishwakarma Chapter 12: Use of synthetic GPIs as anti-toxic vaccine Peter Seeberger Chapter 13: ER export and GPI-proteins Howard Riezman Chapter 14: Polarized sorting of GPI proteins Chiara Zurzolo Chapter 15: Involvement of GPIs in yeast cell wall structure Peter N. Lipke Chapter 16: Paroxysmal nocturnal hemoglobinuria (PIGA mutation) Lucio Luzzatto Chapter 17: Inherited GPI deficiency Anastasios Karadimitris Chapter 18: Inhibitors of GPI biosynthesis Terry K. Smithshow more

About Anant Kumar Menon

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997. Since 1996, he has been a Director of Signal Transduction Program Area at Jonsson Comprehensive Cancer Center. Dr. Tamanoi earned his B.S. and M.S. in Biochemistry at the University of Tokyo. He received PhD in Molecular Biology at Nagoya University in 1977. He was a postdoctoral fellow at Harvard Medical School, where he worked on bacteriophage DNA replication. From 1980 to 1985, he was a senior staff investigator at Cold Spring Harbor Laboratory, where he worked on adenovirus DNA replication. From 1985 to 1993, he was an Assistant Professor and then Associate Professor at the University of Chicago, where he initiated studies on lipid modification of the Ras family proteins. His laboratory research centers on signal transduction and signal transduction inhibitors. He is currently exploring ways to deliver signal transduction inhibitors using nanoparticles.show more