Genome Research in Molecular Medicine and Virology

Genome Research in Molecular Medicine and Virology

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Reviews the application of the techniques of molecular genetics and molecular biology to biomedical research. Among the subjects discussed are normal and abnormal chromosomes, cancer, hereditary disorders, model genome systems and molecular virology. This volume emphasizes: genome research - DNA sequences and gene structure of chromosomes; molecular medicine - gene therapy, cancer research, oncogenes, hereditary disorders, normal DNA and model systems; virology - retroviruses, herpesviruses and poliovirus.
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Product details

  • Hardback | 347 pages
  • 158.75 x 230 x 25.4mm | 683g
  • Academic Press Inc
  • San Diego, United States
  • English
  • index
  • 0120443007
  • 9780120443000

Table of contents

Normal DNA sequence variation - detection technologies and implications, G. Ruano, et al; chromosome mapping using yeast artificial chromosome and cosmid clones, D.L. McElligott and G.A. Evans; gene transfer techniques for use in human gene therapy, P. Tolstoshev and W.F. Anderson; molecular biology of human cancer, C.E. Gauwerky and C.M. Croce; molecular analysis of Angelman and Prader-Willi syndromes, M. Lalande, et al; structure, evolution, and expression of tropomyosin gene family, S. Forry-Schaudies and S.H. Hughes; detection of nucleotide sequence changes by single-strand conformation polymorphism analysis, T. Sekiya; Drosophila as model organism in genome analysis, D.L. Hart and M.J. Palazzolo; organization of chromosomes in chinese hamster cells through mitosis - comparison with HeLa cells, K.W. Adolph; growth factor receptor-dependent signal transduction - targets for design of treatment approaches in medical oncology, F. Foss and E.A. Sausville; use of pulsed-field gel electrophoresis for construction of megabase map of human genome - analysis of human c-myb locus, J-G. Park and E.P. Reddy; family of ETS genes as transcriptional regulatory factors, S. Sorscher, et al; genome analysis using promotor trap retroviruses, H. von Melchner, et al; complexities of human retrovirus gene expression, C.A. Rosen, et al; retroviral RNA, R. Aronoff and M.L. Linial; application of genetic engineering to study of organization and function of herpes simplex virus genes, B. Roizman; latent phase transcription by alphaherpesviruses, M.K. Rice, et al; receptor for poliovirus and other picornaviruses, A. Zibert and E. Wimmer.
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