Genes and the Environment

Genes and the Environment

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Description

"Genes and the Environment" is concerned with genes and how their structures and activities can be influenced by environmental adversities such as toxic industrial chemicals, ultraviolet light, temperature extremes, ionising radiation, food contaminants, and atmospheric contaminants including tobacco smoke. Such interactions are of wide-reaching significance for the mechanisms of adaptation and acclimation. It is also clear that they are very relevant to the development of a number of important diseases such as cancer and to the processes that contribute to our ageing. It is now possible to study the molecular biology of environmental influences on specific genes, which can have profound effects in terms of disease or long-term survival. Moreover many environmental factors are now known to greatly influence the extent to which specific genes are activated to produce proteins that are protective and which enable organisms to survive, or acclimate to particular stresses.show more

Product details

  • Hardback | 256 pages
  • 189 x 246 x 19.05mm | 698g
  • Taylor & Francis Ltd
  • London, United Kingdom
  • English
  • 84ill.16tabs.
  • 0748408274
  • 9780748408276

Table of contents

1. Introduction: Genes and the Impact of the Environment Part One: Gene Damage: Its Limitation, Repair and Consequences 2. Environmental Factors that Damage DNA 3. Spontaneous Alterations to DNA 4. Possible Oxidative DNA Damage from Cellular Free Radicals 5. Detoxification and Antioxidant Defenses 6. DNA Repair Mechanisms 7. Genetic Information Flow 8. DNA Damage, Mutation, Cancer and Ageing, Part Two: Environmental Stress: Genomic Responses 9. Gene Activation and Environmental Stressshow more

About R.H. Burden

Burdon; Roy H. University of Strathclyde, Scotland,show more