Fundamentals of Preparative and Nonlinear Chromatography

Fundamentals of Preparative and Nonlinear Chromatography

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Non-linear chromatography has become an important separation technique for preparitive and process-scale chromatographic applications in industry. This text provides a consolidated summary of the parameters necessary to the optimization of preparative chromotography, with detailed information on the design, economics and critical parameters of preparative separations. The illustrations turn difficult mathematics into easily understood pictures. The concepts outlined are illustrated through numerous examples.
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Product details

  • Hardback | 701 pages
  • 196 x 241 x 38mm | 1,461g
  • Academic Press Inc
  • San Diego, United States
  • English
  • illustrations, glossary, index
  • 012305530X
  • 9780123055309

Table of contents

Introduction, Definitions, Goal. The Mass Balance Equation of Chromatography and Its Properties. Single-Component Equilibrium Isotherms. Competitive Equilibrium Isotherms. Fundamentals of Transfer Phenomena Involved in Chromatography. Linear Chromatography. The Ideal Model of Chromatography: Elution of Single Component Bands. The Ideal Model of Chromatography: Elution of Two-Component Bands. The Ideal Model of Chromatography: Displacement Chromatography. The Equilibrium-Dispersive Model: Elution of Single-Component Bands. The Equilibrium-Dispersive Model: Isocratic Separations of Two-Component Bands and Gradient Elution. The Equilibrium-Dispersive Model: Frontal Analysis and Displacement. The Equilibrium-Dispersive Model: System Peaks in Chromatography. The Kinetic Models: Frontal Analysis and Elution of Single Component Bands. The Kinetic Models: Frontal Analysis, Elution and Displacement of Multicomponent Bands. Optimization of the Experimental Condition in Preparative Chromatography.
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Review quote

"It is this synergy between fundamental understanding and practical realization that is the message of this text. As a result, this book would be a worthwhile and welcomed addition to university and industrial libraries alike. There are many sacrifices involved in writing a book and sometimes the end product is not worth the effort consumed. That is not true in this case and the authors are to be congratulated for a job well done...This book will be a library staple for many years to come and is a good investment for the curious and serious practitioners of chromatography, particularly those interested in process and large scale separations."
--Colin F. Poole, Analytical Chimica ACTA, Vol. 302
"I would add that this book is useful for all who want to have a general understanding of chromatography. There is a good balance between theory, modelling and experimental data and it contains a considerable amount of original work....They make an admirable effort to clearly describe the fundamentals and the assumptions of the different models before writing the corresponding equations."
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