Excitatory Amino Acids and Synaptic Transmission

Excitatory Amino Acids and Synaptic Transmission

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The excitatory amino acids (EAAs) as neurotransmitters are of vast and rapidly expanding interest. This volume relates current knowledge of the EAAs back to the synapse, where many of their physiologically relevant actions must occur. Excitatory Amino Acids and Synaptic Transmission is the first book to do so. A multinational team of experts have contributed not only novel, but in some cases, controversial material, reflecting the competition between research groups on both sides of the Atlantic.
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Product details

  • Hardback | 480 pages
  • 174.5 x 251.2 x 30.7mm | 1,074.91g
  • Academic Press Inc
  • San Diego, United States
  • English
  • glossary, references
  • 0127460306
  • 9780127460307

Table of contents

Part 1 EAA receptor types: excitatory amino acid receptors - multiplicity and structural requirements for activation and blockade, P. Krogsgaard-Larsen et al; excitatory amino acid receptor distribution - quantitative autoradiographic studies, A. B. Young et al; excitatory amino acid receptor heterogeneity, radioligand binding evidence, D. T. Monaghan and K. J. Anderson; quisqualate/AMPA preferring configurations on non-NMDA receptors, T. Honore; excitatory amino acid gated channel types in mammalian neurons and glia, S. G. C. Candy et al; molecular properties of non-NMDA excitatory amino acid receptors, J. M. Henley and E. A. Barnard. Part 2 Channel kinetics: inhibition of the NMDA response at the glycine site and the intracellular MG2+ channel blocking site, J. W. Johnson; desensitizational NMDA and AMPA receptors, M. L. Mayer et al. Part 3 EPSPs/EPSCs: recurrent excitatory synapses between CA3 neurones in the hippocampus, R. Miles et al; excitatory amino acid transmitter function in mammalian central pathways, T. E. Salt and T. L. Herrling; amino acid mediated EPSCs, F. A. Edwards and P. Stern; presynaptic receptors at a central excitatory synapse, I. D. Forsythe; synaptic transmission at unitary CA3-CA1 connections in the hippocampus, R. J. Sayer et al. Part 4 Glial cells: patch-clamp studies of electrogenic glutamate uptake - ionic dependence, modulation, and failure in anoxia, D. Attwell et al. Part 5 Epileptiform activity: excitatory amino acid receptor sub-types and their roles in epileptiform synaptic potentials in the hippocampus, H. V. Wheal et al; (part contents)
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Review quote

"Howard Wheal and Alex Thompson have generated a valuable panorama of glutamate neurobiology in Excitatory Amino Acids and Synaptic Transmission... The book is timely and intelligent overview of neurobiology and should be a valuable resource." --SCIENCE
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