Eukaryotic Transcription Factors
Intended for final year undergraduate and postgraduate students in molecular biology and biochemistry, this book discusses in detail information currently available on transcription factors, emphasizing common motifs, themes and mechanisms. It summarizes the major families, describes the mechanics of activation and repression of eukaryotic genes by transcription factors, and explains the relationship between the structure and function of these factors. Furthermore, it highlights the importance of transcription factors during the development, differentiation and transformation of eukaryotic cells, and provides the principles behind the methods employed to study transcription factors in vivo and in vitro.
- Hardback | 288 pages
- 152.4 x 228.6 x 17.78mm | 408.23g
- 01 Dec 1991
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
Table of contents
DNA sequences and transcription factors; methods for studying transcription factors; RNA polymerase; transcription factors and inducible gene expression; transcription factors and cell type-specific transcription; transcription factors and developmentally regulated gene expression; transcription factors and cancer; DNA binding by transcription factors; activation and repression of gene expression by transcription factors; what activates the activators?; conclusions and future prospects.