Ethambutol

Ethambutol

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Description

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Ethambutol (commonly abbreviated EMB or simply E) is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide. It is sold under the trade names Myambutol and Servambutol. Ethambutol is bacteriostatic against actively growing TB bacilli. It works by obstructing the formation of cell wall. Mycolic acids attach to the 5'-hydroxyl groups of D-arabinose residues of arabinogalactan and form mycolyl-arabinogalactan-peptidoglycan complex in the cell wall. It disrupts arabinogalactan synthesis by inhibiting the enzyme arabinosyl transferase. Disruption of the arabinogalactan synthesis inhibits the formation of this complex and leads to increased permeability of the cell wall.show more

Product details

  • Paperback | 100 pages
  • 152 x 229 x 6mm | 159g
  • Dicho
  • United States
  • English
  • 6135833073
  • 9786135833072