Introduction: Estonian Science Studies; R. Vihalemm. Part I: Studies in the History and Policy of Science in Estonia. Newton's Principia in the Curricula of the University of Tartu (Dorpat) in the Early 1690-s; UE. Lumiste, H. Piirimae. A University Between Two Cultures: On the Development of Tartu/Dorpat University in the 19th and Early 20th Centuries; H. Tankler. The Emergence of Physical Chemistry: The Contribution of the University of Tartu; V. Past. In Political Draughts Between Science and the Humanities: Geography at the University of Tartu Between the 17th-20th Centuries; O. Kurs, E. Tammiksaar. Formation of R&D Policy in a Small Country in a Changing World; H. Martinson. Science and Society - Faculties Close or Apart?; J. Engelbrecht. Part II: Studies in the General Methodology, History and Philosophy of Science. Some Fundamental Criteria of the Scientific Method and the Internal Structure of Science; V. Palm. The Glory and Misery of Modern Science; U. Uus. Edmund Husserl Pursuing the Paths of Descartes: The Paris Lectures on Philosophy as a Universal Science; UE. Matjus. Herman Boerhaave - Communis Europae Praeceptor: Internal vs. External in the History of Science; E. Lohkivi. The Problem of the Relationship Between Human and Physical Realities in Ilya Prigogine's Paradigm of Self-Organisation; L. Napinen. Science and Magic: Causality; P. Muursepp. Symmetry and Rationality; J. Tammaru. Chemistry as an Interesting Subject for the Philosophy of Science; R. Vihalemm. Part II: Studies in the Philosophy of Physics. Physical Reality, Theoretical Physics, and Mathematics; P. Kuusk. Outsolutions in Physical Theories. PhysicalConsiderations; J. Eintalu. What is Time?; M. Koiv, P. Kuusk. The Copenhagen Interpretation of Quantum Mechanics and Common Sense; A. Unt. Part IV: Studies in the Methodology and Philosophy of Special Fields of Research. Knowledge, Human Interests and Migration Studies; H. Kulu. Value-Neutral Paternalism; V. Parve. Inter-Level Explanation and the Category-Mistake; B. Moelder. On the Raising of a Hand; J. Kivistik.