Essentials of Restenosis
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Essentials of Restenosis : For the Interventional Cardiologist

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Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists.show more

Product details

  • Hardback | 488 pages
  • 186.69 x 257.81 x 24.64mm | 1,220.16g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • 38 black & white tables, biography
  • 1588294919
  • 9781588294913

Review quote

From the reviews: "This is a comprehensive review of the problem of restenosis, from the basic science to clinical management. ... The audience includes interventional cardiology fellows and interventional cardiologists. The book describes the difficulties that cardiologists face trying to prevent and manage restenosis. ... Each chapter includes extensive references. This is a complete, state-of-the-art review of restenosis, covering all aspects of restenosis from pathophysiology to therapeutic management. The authors are leaders in interventional cardiology with extensive clinical experience in the field." (Adriana Maria Rosario, Doody's Review Service, December, 2007) "A multiauthored, comprehensive compendium of virtually all aspects of the restenotic process after balloon- or stent-induced arterial injury. ... The text is written by a blueribbon panel of authors who provide an in-depth coverage of the topics. Many of the clinical chapters offer an excellent historical perspective on the problem of restenotis. ... Recommended Readership: Interventional (clinical and research) cardiologists and interventional fellows." (John F. Bresnahan, Mayo Clinic Proceedings, Vol. 83 (4), April, 2008)show more

Back cover copy

Essentials of Restenosis provides the practicing cardiologists and biologists an elaborate review of the current advances in the field. Authors explore the process of restenosis from bench to bedside, encompassing in equal detail the newest scientific findings of the biological mechanisms as well as the progression in development of diagnostics and treatments. The volume also provides the reader with a basic understanding of the biological process and the latest diagnostics and treatments of the disease, with an up-to-date detailed discussion of the most important recent findings. Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists. Thorough chapters discuss the current understanding on the pathophysiology, molecular and genetic base, and methods of diagnosis of restenosis, and present the current state-of-the-art management, including pharmacotherapy and interventional percutaneous approaches using brachytherapy, gene therapy and drug eluting stent technology. All this makes Essentials of Restenosis an excellent handbook for introducing new intervention cardiologists, vascular biologists, and medical students into the subject. This text provides the reader with a complete overview of the basic and applied knowledge of restenosis, leading to better insight and decision-making in clinical practice.show more

Table of contents

Essentials of Restenosis for the Interventional Cardiologist Table of Contents: Part A. Introduction Henricus J. Duckers Caroline Cheng Dennie Tempel Patrick W. Serruys Part B. Pathophysiology and Diagnosis Chapter: 1. Epidemiology and Pathogenesis of Restenosis Randolph L. Geary Alexander W. Clowes 2. Clinical Presentation of Restenosis Ganesh Manoharan Giedrius Davidavicius William Wijns 3. Pathologic Anatomy of Restenosis Renu Virmani Frank D. Kolodgie Aloke V. Finn Herman K. Gold 4. The Influence of Shear Stress on Restenosis Attila Thury Cornelis J. Slager et al. 5. Role of the Immune System in the Pathogenesis of Vascular Proliferative Disease Jon D. Laman Burkhard Ludewig 6. Animal Restenosis Models. From the a oeIdeal Modela ? to the a oeIdeal Studya ? Arturo G. Touchard Robert S. Schwartz Part C. Genetic base of restenosis Chapter: 7. The Genomics of Restenosis Thomas W. Johnson Karl R. Karsch 8. Gene Expression Profiling and Restenosis Dietlind Zohlnhofer Franz-Josef Neumann 9. Proteomics and Restenosis Santhi K. Ganesh Elizabeth G. Nabel 10. Contribution of circulating Progenitor Cells to Vascular Repair and Lesion Formation. Masataka Sata Kenneth Walsh 11. Cell Cycle Regulation in Vascular Proliferative Diseases Andrew Wragg Manfred Boehm 12. Arterial Remodelling Gerard Pasterkamp Bradley H. Strauss Dominique de Kleijn 13. The role of eNOS in vascular diseases Alexey Kuroedov Francesco Cosentino Felix C. Tanner Thomas Luscher Part D. Diagnostics of Restenosis Chapter: 14. The use of pressure gradient analysis in the diagnosis of restenosis Volker Klaus Nico N.H.J. Pijls 15. The Use of Radio Isotopes in the Diagnosis ofVascular Proliferative Disease Giedrius Davidavicius Ganesh Manoharan William Wijns 16. Magnetic resonance imaging for restenosis Robert Jan M. van Geuns Timo Baks 17. Coronary Imaging with Multislice Spiral Computed Tomography Koen Nieman Part E. Therapy of Restenosis Chapter: 18. Pharmacotherapy of Restenosis Pim J. de Feyter Georgios Sianos 19. Brachytherapy Ron Waksman 20. Pre-clinical Data of Eluting Stents Antonio Colombo Alaide Chieffo 21. Clinical Data of Eluting Stents Marco A. Costa Alexandre Abizaid Amanda G.M.R. Sousa Eduardo Sousa 22. Biodegradable stents Takafumi Tsuji Hideo Tamai Keiji Igaki Part F. Biotechnology in the Treatment of Restenosis Chapter: 23. Vascular Gene Therapy Gurpreet S. Sandhu Robert D. Simari 24. Antisense and ODN transcription factors in the treatment of Vascular Proliferative Disease Nicholas Kipshidze Mykola Tsapenko George Dangas Pat Iversen 25. Cell Cycle Approaches to the Treatment of In-stent Restenosis Elizabeth G. Nabel 26. Local Gene and Cell Delivery Devices Ravish Sachar Eric J. Topolshow more

Review Text

From the reviews: "This is a comprehensive review of the problem of restenosis, from the basic science to clinical management. ... The audience includes interventional cardiology fellows and interventional cardiologists. The book describes the difficulties that cardiologists face trying to prevent and manage restenosis. ... Each chapter includes extensive references. This is a complete, state-of-the-art review of restenosis, covering all aspects of restenosis from pathophysiology to therapeutic management. The authors are leaders in interventional cardiology with extensive clinical experience in the field." (Adriana Maria Rosario, Doody's Review Service, December, 2007) "A multiauthored, comprehensive compendium of virtually all aspects of the restenotic process after balloon- or stent-induced arterial injury. ... The text is written by a blueribbon panel of authors who provide an in-depth coverage of the topics. Many of the clinical chapters offer an excellent historical perspective on the problem of restenotis. ... Recommended Readership: Interventional (clinical and research) cardiologists and interventional fellows." (John F. Bresnahan, Mayo Clinic Proceedings, Vol. 83 (4), April, 2008)show more