Essential Chemistry for Formulators of Semisolid and Liquid Dosages

Essential Chemistry for Formulators of Semisolid and Liquid Dosages

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Description

A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.
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Product details

  • Hardback | 256 pages
  • 152 x 229 x 19.05mm | 570g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 012801024X
  • 9780128010242

Table of contents

1. Introduction to the Chemistry of Mixing
2. Surfactants, Lipids and Surface Chemistry
3. Drug Delivery Vehicles
4. Formulating Creams, Gels, Lotions and Suspensions
5. Polymers and Thickeners in Semisolid Formulations
6. Topical Aerosol and Nasal Sprays
7. Formulation and Stability Testing
8. Particle Size: An Overview of Various Methods
9. Rheological/Viscosity Studies
10. Microscopy Techniques (Optical and Electron Microscopy)
11. Miscellaneous Physical, Chemical and Microbiological Test Methods
12. An Overview of Regulatory Aspects for Pharmaceutical Semisolid Dosage
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About Charles Shaw

Vitthal Kulkarni, Ph.D. is Scientific Advisor at DPT Laboratories San Antonio, Texas. After earning Ph.D. in Chemistry at National Chemical Laboratory, Pune, India in the area of surface/colloid chemistry, Dr. Kulkarni studied lipid monolayers, bilayers, self-assembled nano-structures, and protein electron crystallography at various institutions including Universite de Provence, Marseille, France, JEOL Ltd., Tokyo, Japan, Vanderbilt University, Nashville, Tennessee, University of Minnesota, Austin, Minnesota and Yale University, New Haven, Connecticut before moving into industry. Dr. Kulkarni has been with DPT Laboratories since 2003.Dr. Kulkarni is experienced in developing and characterizing various non-invasive drug delivery systems including topical drug delivery systems comprised of liposomes, and nano-particles, emulsions and nasal spray products. He has published scientific research articles in peer reviewed journals, patents, book chapters, and edited a book titled Handbook of Non-Invasive Drug Delivery Systems: Science and Technology. He is a current member of American Association of Pharmaceutical Scientists. Charles Shaw, Ph.D. is Scientific Advisor at DPT Lakewood LLC, Lakewood, NJ. Dr. Shaw has more than 30 years of experience in pharmaceutical and medical device development and manufacturing, and holds board certifications that include Chartered Scientist; Chartered Chemist; Fellow of the Royal Society of Chemistry, London; and European Chemist. Before joining DPT Laboratories in 2004, he was Product Development and Technical Services Manager with Smith & Nephew Medical Ltd. He earned a Ph.D. in Chemistry at the University of Hull, England in the area of reaction kinetics.Dr. Shaw is experienced in the development and characterization of wound dressings, semi-solid and liquid formulations, and nasal spray products. He has published scientific research articles in peer reviewed journals, book chapters, trade journals and conferences. He has also presented webinars and conference workshops for nasal spray products. He is a current member of American Association of Pharmaceutical Scientists.
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