Emerging Applications of Molecular Imaging to Oncology: Volume 124

Emerging Applications of Molecular Imaging to Oncology: Volume 124 : Emerging Applications of Molecular Imaging to Oncology

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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume, number 124, covers emerging applications of molecular imaging to oncology, including molecular-genetic imaging, imaging the tumor microenvironment, tracking cells and vaccines in vivo, and more.
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Product details

  • Hardback | 402 pages
  • 154 x 232 x 28mm | 619.99g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0124116388
  • 9780124116382

Table of contents

1. Quantitative Radiology: Applications to Oncology
Edward H Herskovits
2. The Intricate Role of CXCR4 in Cancer
Samit Chatterjee, Babak Behnam Azad and Sridhar Nimmagadda
3. Recent Advances in Nanoparticle Based Nuclear Imaging of Cancers
Avinash Srivatsan and Xiaoyuan Chen
4. Molecular-Genetic Imaging of Cancer
Il Minn, Mitchell E. Menezes, Siddik Sarkar, Keerthi Yarlagadda, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Paul B. Fisher and Martin G. Pomper
5. Real-Time Fluorescence Image-Guided Oncologic Surgery
Suman B. Mondal, Shengkui Gao, Nan Zhu, Rongguang Liang, Viktor Gruev and Samuel Achilefu
6. Cerenkov imaging: seeing the light
Sudeep Das and Jan Grimm
7. Molecular Imaging of the Tumor Microenvironment for Precision Medicine and Theranostics
Marie-France Penet, Balaji Krishnamachary, Zhihang Chen, Jiefu Jin and Zaver M. Bhujwalla
8. Tracking Cellular and Immune Therapies in Cancer
David M. Kurtz and Sanjiv S. Gambhir
9. Developing MR probes for Molecular Imaging
Michael T. McMahon and Kannie W.Y. Chan
10. Clinical Translation of Molecular Imaging Agents used in PET Studies of Cancer
Laura M. Kenny and Eric O. Aboagye
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Review quote

"...provides invaluable information on the exciting and fastmoving field of molecular imaging in oncology. This book offers ten authorative reviews on the topic..."--Anticancer Research, February 2015
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About Martin G. Pomper

Paul B. Fisher, M.Ph., Ph.D., is an accomplished molecular biologist investigating the mechanisms involved in cancer development and progression in order to define improved methods for cancer prevention, detection and therapy. Fisher pioneered a powerful technique to study gene expression in specific tissues or cell types known as subtraction hybridization, which he has used to identify genes involved in many important and medically relevant physiological processes including cancer, neurodegeneration and infectious diseases. Studies in his laboratory focus on understanding the molecular and biochemical reasons for cancer development with a specific focus on understanding how cancers spread, a process called metastasis. The ultimate aim is to use this collected knowledge to bring new, more effective prevention techniques, diagnostic approaches and therapies from the laboratory bench to the patient's bedside. This is epitomized by his studies involving mda-7/IL-24, a gene that was discovered in his laboratory and has displayed significant clinical efficacy in a phase 1 clinical trial when injected directly into advanced cancers using a form of viral gene therapy. Using a novel cancer terminator virus, Ad.5/3-CTV, that is designed to replicate only within cancer cells while delivering the immune-modulating and toxic mda-7/IL-24 gene, Fisher and his clinical colleagues are developing a clinical trial in patients with glioblastoma multiforme, the most common and deadly form of brain cancer. Fisher has been consistently funded by the National Institutes of Health (NIH) over the past 35 years and is among the top 5 percent of NIH funded investigators during this period. He has published over 500 primary papers and reviews, served on numerous NIH study sections and government and private grant review panels and has over 55 issued patents. He is the recipient of multiple National Cancer Institute (NCI) Program Project Grants; investigator initiated R01 grants from the NIH, NCI and National Institute of General Medical Sciences (NIGMS); private foundation grants from the National Foundation for Cancer Research and the Samuel Waxman Cancer Research Foundation; and an Institutional Research and Academic Career Development Award from the NIH focusing on preparing students from groups underrepresented in the sciences for research careers. Fisher is Professor and Chair of the Department of Human and Molecular Genetics at the Virginia Commonwealth University (VCU) School of Medicine, Founding Director of the VCU Institute of Molecular Medicine and Thelma Newmeyer Corman Chair in Cancer Research and co-leader of the Cancer Molecular Genetics research program at VCU Massey Cancer Center.
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