ECAT Assay Procedures : Manual of Laboratory Techniques - European Concerted Action on Thrombosis and Disabilities of the Commission of the European Communities
Offering a description of current and recently developed laboratory assays in the field of haemostasis and thrombosis, this work is the result of a co-operation between experts from more than 60 institutes in 12 European countries, brought together by the ECAT (European Concerted Action on Thrombosis and Disabilities) under the auspices of the Commission of the European Communities in Brussels. The work is based on two previous editions, which were for internal use only. Each assay was assessed by an expert who functioned in the ECAT as representative of a reference laboratory. An assay committee co-ordinated the activities, and each chapter is written by an assay expert. Most of the chapters give descriptions of the assay recommended for use in the ECAT and briefly mention alternatives. For this reason, a list is included of firms that are commercializing kits and reagents. The book aims to contribute to further harmonization of haemostasis assays and, ultimately, to their standardization.
- Hardback | 240 pages
- 165.1 x 240 x 19.05mm | 539.96g
- 01 Apr 1992
- Kluwer Academic Publishers
- Dordrecht, Netherlands, United States
Table of contents
Quality assessment of haemostatic assays, S.G. Thompson and J.M. Thomson; blood collection and preparation - pre-analytical variation, J.M. Thomson; beta-thromboglobulin and platelet factor 4, D.S. Pepper and C.V. Prowse; the activated partial thromboplastin time (APTT), L. Poller and J.M. Thomson; the prothombin time test, L. Poller; fibrinogen, G.A. Marbet and F. Duckert; factor VII clotting activity, G.A. Marbet and F. Duckert; factor VIII clotting activity, P.M. Mannucci and A. Tripodi; Von Willebrand factor, P.M. Mannucci and R. Coppola; antithrombin III activity and antigen, J. Conard; protein C activity and antigen, R.M. Bertina; protein S antigen, R.M. Bertina; fibrinopeptide A (FPA), A. Haeberli; thrombin-antithrombin III complexes, J. Harenberg; euglobulin clot lysis time, E. Preston and P.C. Cooper; tissue type plasminogen activator antigen (t-PA Ag), P. Juhan-Vague and M.C. Alessi; tissue-type plasminogen activator activity assay, J.H. Verheijen; plasminogen activator inhibitor activity assay, E.K.O. Kruithof; plasminogen activator inhibitor antigen assay, E.K.O. Kruithof; plasminogen activity, P.J. Gaffney; alpha-2-antiplasmin activity, C. Kluft; plasmin-alpha-2-antiplasmin complexes, E. Hattey et al; plasma histidine-rich glycoprotein (HRG), J. Gram; quantitative enzyme immunoassays for degradation products of fibrinogen (FgDP), fibrin (FbDP) and total of FgDP and FbDP (TDP), W. Nieuwenhuizen; B-beta 15-42 peptide, A. Haeberli; vein occlusion test, J. Jespersen.