Drug Interactions in Infectious Diseases

Drug Interactions in Infectious Diseases

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Theory of Contents: Section 1: General Concepts - Introduction to Drug Interactions, Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion, Mechanisms of Drug Interactions II: Transport Proteins, and Drug-Food Interactions. Section, Drug Classes - Antiretrovirals, Non-HIV Antivirals, Rifamycins and other Anti-Tubercular Agents, Macrolides, Azolides, and Ketolides, Quinolones, Beta-Lactam Antibiotics, Antifungal Agents, Antimalarial Agents, Antiprotozoal and Antithelmintic Agents, Glycopeptides and Lipopeptides, Tetracyclines, Aminoglycosides and Miscellaneous Antibiotics, Drug-Cytokine Interactions, and Drug Interactions with Herbal/Alternative Medicines. Section 3: Research Issues - Drug Interactions: Regulatory Perspective, Probe Cocktail Studies, and Design and Data Analysis of Drug Interaction Studies.show more

Product details

  • Hardback | 548 pages
  • 184 x 258 x 38mm | 1,261g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • Revised
  • 2nd Revised edition
  • 3 black & white illustrations
  • 1588294552
  • 9781588294555

Review quote

From Reviews of the First Edition... "...an invaluable reference source for health practitioners working in the field of infectious diseases..." -Journal of Antimicrobial Chemotherapy "...an interesting and extensively referenced book that should prove extremely helpful to pharmacists, pharmacologists, and medical educators...can also benefit ID clinicians, as a useful reference and a review of the mechanisms of drug interactions." -Clinical Infectious Diseases "...a useful and impressive book...an essential reference source." -British Journal of Clinical Pharmacology "...recommend[ed] to anyone involved in the management of infectious disease." -Transactions of the Royal Society of Tropical Medicine "...highly recommended for all medical collections." -E-Streams "...a valuable text for all practitioners involved in using anti-infective agents...provide[s] insight into the very important issue of drug interactions." -Doody's Health Sciences Book Review Journal "...excellently presented and readable." -BTS Newsletter "...superior." -BTS Newslettershow more

Back cover copy

Now extensively revised and significantly expanded, this second edition of the highly praised Drug Interactions in Infectious Diseases includes all the major recent advances in the understanding of drug interactions, with particular emphasis on the many new drugs approved since the first edition. The treatment of drug interaction mechanisms has increased to fill two chapters, allowing a more detailed description of absorption, metabolism, and excretion, as well as describing the growing knowledge of transport proteins. Recent reports of drug interactions, new case studies, and a new chapter outlining the regulatory perspective on interaction studies during drug development have been added. The chapter on study design and data analysis remains one of the best of its kind. The information contained in the book ranges from detailed tables of specific drug-drug interactions to in-depth discussions of interaction mechanisms and research issues. Comprehensive and up-to-date, Drug Interactions in Infectious Diseases, Second Edition concisely and authoritatively summarizes-for rapid access by all health care practitioners-the important drug interactions that occur during the treatment of infectious diseases, the mechanisms of their action, and the best strategies for their management in patient care.show more

Table of contents

Introduction to Drug Interactions Keith Gallicano and George Drusano Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion Angela D. M. Kashuba and Joseph S. Bertino, Jr. Mechanisms of Drug Interactions II: Transport Proteins Scott R. Penzak Drug Interactions: Regulatory Perspective Kellie Schoolar Reynolds Drug Interactions With Antiretrovirals for HIV Infection Kimberly A. Struble and Stephen C. Piscitelli Drugs for HIV-Related Opportunistic Infections Alice Tseng Drugs for Tuberculosis Rocsanna Namdar, Steven C. Ebert, and Charles A. Peloquin Quinolones David R. P. Guay b-Lactam Antibiotics Melinda M. Neuhauser and Larry H. Danziger Antifungal Agents Paul O. Gubbins, Scott A. McConnell, and Jarrett R. Amsden Miscellaneous Antibiotics Gregory M. Susla Drug-Food Interactions Kelly A. Harris, Kevin W. Garey, and Keith A. Rodvold Drug-Cytokine Interactions Curtis E. Haas and Jamie L. Nelsen Circumventing Drug Interactions Douglas N. Fish Design and Data Analysis of Drug Interaction Studies David E. Nix and Keith Gallicano Indexshow more