The Doc and the Duchess
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The Doc and the Duchess : The Life and Legacy of George H. A. Clowes

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George Henry Alexander Clowes was a pivotal figure in the development of the insulin program at the Eli Lilly Company. Through his leadership, scientists and clinicians at Lilly and the University of Toronto created a unique, international team to develop and purify insulin and take the production of this life-saving agent to an industrial scale. This biography, written by his grandson, presents his scientific achievements, and also takes note of his social and philanthropic contributions, which he shared with his wife, Edith. It tells the story of Clowes from his childhood in late Victorian England to his death at Woods Hole on Cape Cod in 1958. Educated in England and Germany, Clowes came to America to join a startup laboratory in Buffalo, where he conducted basic research on cancer and applied research on other disease-related problems. Assuming the position of head of research at Lilly, Clowes was at the center of one of the great discoveries that changed the course of medical history and offered new life to millions of individuals with diabetes and other metabolic disorders. Clowes was also instrumental in the development of other commercial pharmaceutical advances. Devoted to a number of philanthropic causes, Clowes and Edith contributed greatly to the cultural life of his adopted country, a contribution that continues to this day.show more

Product details

  • Hardback | 232 pages
  • 152 x 229 x 22.86mm | 467g
  • Indiana University Press
  • Bloomington, IN, United States
  • English
  • 20 b&w illus.
  • 0253020425
  • 9780253020420

Review quote

The Doc and the Duchess is . . . a labor of love and yet another treasure that the Clowes family has bequeathed to the Indianapolis community. * Indiana Magazine of History * The book is written in a clear but engaging manner, neither fawning nor clinical. Readers should find it informative and enlightening, showing the personal lives behind some very public endeavors. * The Franklin Daily Journal *show more

About Alexander W. Clowes

Alexander W. Clowes (1946-2015), vascular surgeon, internationally renowned scientist in vascular biology, teacher and mentor, held the Gavora-Schilling Endowed Chair of Vascular Surgery at the University of Washington School of Medicine. Clowes was a Director and President of The Clowes Fund.show more

Table of contents

Foreword / John LechleiterAcknowledgementsIntroduction: A Warm Embrace1. Growing Up in Victorian England2. The Search for a Cure of Cancer3. Edith Whitehill Hinkel 4. Alec and Edith5. 1914: The End of an Era6. In the Borderline Fields of Medicine 7. Lilly and the Insulin Story8. From Small to Large Scale Production of Insulin9. Expansion of the Research Programs10. Woods Hole, MBL, and the Pursuit of Cancer11. The Duchess, The Doc and The Boys12. Alec and Edith: Indianapolis Benefactors13. A Legacy: In Others' EyesAppendix I: Publications of George Henry Alexander ClowesAppendix II: Chronology of Ancestry NotesWorks CitedIndexshow more

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