Development of T Cell Immunity: Volume 92

Development of T Cell Immunity: Volume 92

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T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.

This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity.
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Product details

  • Hardback | 342 pages
  • 149.86 x 231.14 x 25.4mm | 612.35g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 92nd edition
  • 0123812844
  • 9780123812841

Table of contents

Development of T cell immunity

The development of T cell immunity - Adrian Liston
The evolution of T cell immunity

Genome duplication and T cell immunity - Masanori Kasahara

Questions arising from "Genome duplication and T cell immunity" - Claude Perreault
Response to questions - Masanori Kasahara

The origin and role of MHC class I-associated self peptides - Claude Perreault

Questions arising from "The origin and role of MHC class I-associated self peptides" - Masanori Kasahara
Response to questions - Claude Perreault

Thymic requirements for T cell immunity

Transcriptional regulation of thymus organogensis and thymic epithelial cell differentiation - Nancy Manley and Brian Condie
Early T cell differentiation: lessons from T-cell acute lymphoblastic leukemia - Cedric S Tremblay, Thu Hoang and Trang Hoang
T cell immunity in the periphery

Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses - Peter J L Lane, Fiona M McConnell, David Withers, Fabrina Gaspal, Manoj Saini and Graham Anderson

Commentary on "Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses" - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes

Cellular and Molecular Requirements in Lymph Node and Peyer's Patch Development - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
T follicular helper cells during Immunity and Tolerance - Michelle A. Linterman and Carola G. Vinuesa
Preventing T cell-dependent autoimmunity

Thymic selection and lineage commitment of CD4+Foxp3+ regulatory T cells - Paola Romagnoli and Joost P.M. van Meerwijk
Molecular Mechanisms of Regulatory T cell Development and Suppressive Function - Jeong M. Kim

Is Foxp3 the master regulator of regulatory T cells? - Adrian Liston
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Review quote

PRAISE FOR THE SERIES: "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal
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About Adrian Liston

Adrian Liston is Professor in Autoimmune Genetics at the University of Leuven and the VIB, Belgium. His PhD research was on T cell tolerance and diabetes with Professor Chris Goodnow at the Australian National University, followed by post-doctoral research on regulatory T cell biology with Professor Sasha Rudensky at the University of Washington. The Liston laboratory is supported by an ERC Start Grant, a JDRF Career Development Award, a VIB Investigators Award and grants from the FWO and KUL. Adrian Liston has published more than 70 papers, with over 3000 citations, including key publications on the function of Aire in thymic tolerance, defective tolerance in the NOD mouse, the contribution of immunodeficiency to autoimmunity, microRNA function in regulatory T cells, the discovery of the follicular regulatory T cell, the role of microRNA in the thymic epithelium and the homeostatic control over regulatory T cells.
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