D1 D2 Dopamine Receptors

D1 D2 Dopamine Receptors

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Few areas in psychopharmacology can have undergone three revisions over a time span so short as that separating recent insights into the function of brain dopamine receptor types. Evidence for an important role for the D-1 receptor has been followed by yet further evidence indicating critical D-1:D-2 interactions in the regulation of psychomotor function. Very recently, molecular biological studies have resulted in the cloning and expression of multiple dopamine receptor proteins, designated D-1 to D-5, that might be accommodated conveniently within the original D- l/D-2 nomenclature as families of 'D-1-like' [D-1A, D-1B, & D-5] and 'D-2-like' [D-2L, D-2S D-3 & D4] receptors. The purpose of the present volume is to present up-to-date, critical reviews of research and theory into the fundamental interactions between these two 'families' or dopamine receptors at a variety of levels of investigation from neurochemistry, molecular biology and neuroanatomy, through electrophysiology, to the psychopharmacology of multiple forms of behaviour and to their clinical significance and therapeutic potential.
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Product details

  • Hardback | 480 pages
  • 149.86 x 228.6 x 7.62mm | 589.67g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0127290451
  • 9780127290454

About John L. Waddington

Edited by John L. Waddington, and Peter Jenner
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Table of contents

Are plant hormones involved tn root to shoot communication? M.B. Jackson. 1. Introduction. 2. The hormone message concept - different kind of hormonal message; quantifying hormonal messages in transpiration stream; assessing developmental impact of hormonal messages. 3. Evidence for regulation of root: shoot ratio by roots - nutrient control theory; shortcomings of nutrient control theory; conclusion. 4. Examples of hormone like action of roots on shoots - early research; leaf senescence; shoot extension, photosynthesis and flowering; conclusions. 5. Cytokinins -.introduction and early research; development in unstressed plants.
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