Current Concepts in Drug Metabolism and Toxicology: Volume 63

Current Concepts in Drug Metabolism and Toxicology: Volume 63

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Description

This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
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Product details

  • Hardback | 304 pages
  • 157.48 x 226.06 x 20.32mm | 544.31g
  • Academic Press Inc
  • San Diego, United States
  • English
  • New
  • 0123983398
  • 9780123983398

Table of contents

Membrane Transporters in Drug Development
The Keap1-Nrf2 Cell Defence Pathway - A Promising Therapeutic Target?
Animal Models of Idiosyncratic Drug Reactions
Genetic Polymorphisms Affecting Drug Metabolism: Recent Advances and Clinical Aspects
Arylamine N-Acetyltransferases - from Drug Metabolism and Pharmacogenetics to Identification of Novel Targets for Pharmacological Intervention
Human Pluripotent Stem Cells for Modelling Toxicity
Disposition of Biologics
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