Coronary Pressure

Coronary Pressure

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Coronary pressure measurement has emerged over the last few years as a major step forward in the invasive assessment of coronary artery disease. This was due on the one hand to major technical progress in developing pressure-monitoring guide wires, and on the other to a theoretical innovation, the concept of coronary pressure-derived fractional flow reserve, which closely relates distal coronary pressure to myocardial blood flow during maximum arteriolar vasodilation. In the catheterization laboratory, this new approach enables an "on-the-spot" diagnosis as to what extent a given epicardial stenosis contributes to reversible myocardial ischemia and the decision as to whether revascularization of the stenosis is warranted or not. In addition, pressure-derived fractional flow reserve appears to be a useful index in monitoring and guiding coronary intervention, including stent deployment. In "Coronary Pressure", the theoretical and physiological background of this approach is systematically reviewed and advanced clinical applications are illustrated, for both diagnostic and interventional catheterization, including tips, tricks, and potential pitfalls of this approach.
This book caters for two types of reader: first, as a guide to the interventionalist who wants to make a quick start; and second, for cardiologists, radiologists, physiologists, and fellows in training for those specialties, who would like to understand the most recent progress in the field of invasive functional assessment of coronary artery disease. This book is an aid to the understanding and treatment of coronary artery disease and could be a major influence on practice in the catheterization laboratory in the next decade.
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Product details

  • Hardback | 368 pages
  • 160 x 241.3 x 20.3mm | 748.44g
  • Dordrecht, Netherlands, United States
  • English
  • 1997 ed.
  • index
  • 0792346726
  • 9780792346722

Table of contents

The coronary circulation; introduction to invasive assessment of the coronary circulation; fractional flow reserve; practical set-up of coronary pressure measurement; validation of fractional flow reserve in animals; validation of fractional flow reserve in humans; independence of fractional flow reserve of hemodynamic loading conditions; fractional flow reserve in normal coronary arteries; fractional flow reserve to distinguish significant stenosis; comparison of fractional flow reserve to non-invasive tests to detect reversible ischemia; assessment of collateral blood flow by coronary pressure measurement; fractional flow reserve for evaluation of coronary interventions; myocardial fractional flow reserve and clinical outcome; clinical cases; conclusions and perspectives for the future.
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Review quote

`It has been the enormous contribution of Drs. Pijls and De Bruyne and their colleagues that they have been able to develop such an approach, that has been further improved, extensively validated and applied in routine practice. ... This book has been written such that both the practical cardiologist who wants to know how to perform the procedure according to the rules, as well as the scientist who wants to know everything about the underlying principles and the results of the validation studies, will find it very useful. In conclusion, this book is a must for the practicing interventionalist as well as the scientist who is interested in coronary and myocardial physiology. The two authors are to be congratulated on writing such a nice and innovative piece of work.'
International Journal of Cardiac Imaging, 14 (1998)
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