Conflicts of Interest in Clinical Practice and Research

Conflicts of Interest in Clinical Practice and Research

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Our society has long sanctioned, at least tacitly, a conflict of interest in medical practice and research as an unavoidable consequence of the different interests of the participants in health care: the physician or clinical researcher, the patient or research subject, insurance companies or research sponsors, the government, and society as a whole. This multidisciplinary effort draws from philosophy, medicine, law, economics and public policy to identify and categorize conflicts of interest in medical practice and clinical research, and, where possible, to offer a mechanism for resolving them. Part I reviews the theoretical background, including basic concepts and analytical frameworks. The second part discusses two topics prominent in current health care policy debates--self-referral and financial incentives to limit care. Part III examines conflicts of interest generated by pharmaceutical industry involvement in clinical practice and research. The final section deals with clinical research in several contexts, including institutional review boards, clinical trials, research agreements between the government and private researchers, brokerage of research subjects by contract research organizations, and cost-effectiveness studies.show more

Product details

  • Hardback | 468 pages
  • 167.6 x 231.1 x 27.9mm | 861.84g
  • Oxford University Press Inc
  • New York, United States
  • English
  • 0195080246
  • 9780195080247

Table of contents

Part I: A Theoretical, Interdisciplinary. and Comparative Perspective. Roy G. Spece, Jr. and David S. Shimm: Introduction. 1: E.L. Erde: Conflicts of Interest in Medicine: A Philosophical and Ethical Morphology. 2: Roy G. Spece, Jr, and David S. Shimm: Discovering the Ethical Requirements of Physicians; Roles in the Service of Conflicting Interests as Healers and as Citizens. 3: Geoffrey C. Hazard, Jr.: Conflicts of Interest in the Classic Professions. 4: Allen E. Buchanan: Is there a Medical Profession in the House?. 5: Charles W. Wolfram: A Trans-Substantive Approach to Conflicts of Interest. Part II: Clinical Practice. 6: Roy G. Spece, Jr. and David S. Shimm: An Introduction to Conflicts of Interest in Clinical Practice. 7: Nancy J. Moore: Entrepreneurial Doctors and Lawyers: Regulating Business Activity in the Medical and Legal Professions. 8: Marc A. Rodwin: Physicians; Conflicts of Interest in HMOs abnd Hospitals. 9: Mark A. Hall: Physician Rationing and Agency Cost Theory. 10: E. Haavi Morreim: Conflicts of Interest for Physician Entrepreneurs. 11: Jay A. Katz: Informed Consent to Medical Entrepreneurialism. 12: Jean M. Mitchell: Physician Joint Ventures and Self Referral: An Empirical Perspective. Part III: The Pharmaceutical Industry's Influence on Clinical Practice and Referrals. 13: Roy G. Spece, Jr., Davis S. Shimm, and Michele Y. Burpeau-DiGregorio: Conflicts of Interest in Relationships Between Physicians and the Pharmaceutical Industry. Part IV: Clinical Research. 14: Roy G. Spece, Jr., and David S. Shimm: An Introduction to Conflicts of Interest in Clinical Research. 15: Edward J. Huth: Conflicts of Interest in Industry-Funded Clinical Research. 16: Baruch A. Brody: Conflicts of Interest and the Validity of Clinical Trials. 17: Thomas L. Kurt: Regulation of Government Scientists' Conflicts of Interest. 18: Leslie Francis: IRBs and Conflicts of Interestshow more