Concepts in Clinical Pharmacokinetics

Concepts in Clinical Pharmacokinetics

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Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers. Inside you will find:* Content broken into 15 easy-to-follow lessons, perfect for a semester.* Practice quizzes in 11 chapters to chart progress.* Four chapters completely devoted to clinical cases.* More information on hemodialysis* More on pharmacogenetics* More on plasma concentration versus time curve (AUC) calculations* A phenytoin "cheat sheet" to help you through the calculations maze* New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations* More on modified diet in renal disease (MDRD) formula versus Cockcroft-Gault (CG) formula methods* More theory and problems on extended interval aminoglycosides.show more

Product details

  • Paperback | 296 pages
  • 213.36 x 276.86 x 15.24mm | 771.1g
  • American Society of Health-System Pharmacists
  • Bethesda, United States
  • English
  • Revised
  • 6th Revised edition
  • 1585283878
  • 9781585283873
  • 867,396

Review quote

Concepts in Clinical Pharmacokinetics, 6th EditionBy William J. Spruill, PharmD, FASHP, FCCP, William E. Wade, PharmD, FASHP, FCCP, Joseph T. DiPiro, PharmD, Robert A. Blouin, PharmD, Jane M. Pruemer, PharmD, BCOP, FASHP, , MedInfoNow: Doody's Review Services[REVIEWER'S EXPERT OPINION] Christina Rose, PharmD (Temple University School of Pharmacy)Description The first half of this thoroughly updated book discusses pharmacokinetic concepts and presents clinical examples and practice questions after each chapter, while the second half applies the pharmacokinetic concepts in chapters on the most commonly dosed drugs in clinical practice. Throughout, there are problems and discussion points, which may be used by instructors in classroom settings. The previous edition was published in 2010. Purpose The purpose is to introduce and explain important pharmacokinetic concepts and then use a stepwise approach to apply these concepts using clinical cases. Pharmacokinetics is a complicated topic that is important for pharmacists and pharmacy students to understand and apply to clinical scenarios. The authors do an exceptional job of explaining the concepts simply and clearly, and each chapter builds on the previous ones to allow the reader to gain a better understanding of the material. Audience Although the target audience appears to be pharmacy students, the book also would serve as a good refresher for residents and general pharmacists and pharmacy practitioners. The authors are all well-known pharmacy educators who are well qualified to write a book on this topic. Features Brief discussions and definitions of concepts related to pharmacokinetics and pharmacodynamics begin the book. The next lessons (chapters) go into more detail about each important pharmacokinetic parameter. The last four lessons review clinical dosing cases using the most commonly monitored drugs in clinical practice. This book presents many opportunities for readers to assess and apply what they have learned from each lesson, with multiple review questions and answers with explanations, as well as three sets of practice questions placed throughout the book to test understanding the of the previous few chapters. The frequent opportunities for assessment and feedback (with answers included) are strengths of this book. Each chapter contains numerous relevant clinical pearls to illustrate important points. The book also contains a glossary of abbreviations, definitions, and a multiple-page equation sheet which would be very helpful to students encountering this material for the first time. Assessment This is a useful reference for pharmacy students or practitioners looking to refresh their knowledge or skills. The material is presented in an easy to understand format, more so than other books on this topic. This update does expand on a few important clinical pharmacokinetic concepts: estimating renal function, extended-interval aminoglycoside dosing, and pharmacogenomics. These expanded sections are brief, yet needed additions. ----------------------------------------------------------- Weighted Numerical Score: 88 - 3 Stars --Christina Rose (Temple University)"MedInfo Doodys Review Services" (07/18/2014)show more

About William J. Spruill

William J. Spruill, PharmD, FASHP, FCCP, is Professor Emeritus in the Department of Clinical and Administrative Pharmacy at the University of Georgia College of Pharmacy and clinical pharmacist at St Mary's Health Care System Inc., Athens, Georgia, USA. Dr. Spruill received his bachelor of science degree in pharmacy from the University of Georgia's College of Pharmacy and completed an American Society of Hospital Pharmacy accredited residency and doctor of pharmacy degree from the Medical University of South Carolina. He is a Fellow of both the American Society of Health-System Pharmacists (FASHP) and College of Clinical Pharmacy (FCCP). He teaches clinical pharmacokinetics at the University of Georgia and offers a 16-week online pharmacokinetics course in conjunction with ASHP and The University of Georgia's Department of Continuing Education. William E. Wade, PharmD, FASHP, FCCP is Emeritus Professor of Pharmacy at the University of Georgia, USA. He received both his bachelor of science in pharmacy and doctor of pharmacy degrees from the University of Georgia's College of Pharmacy. Dr. Wade is a Fellow of the American Society of Health-System Pharmacists and a Fellow of the American College of Clinical Pharmacy. Prior to his retirement, he taught both didactic and experiential clinical pharmacokinetics for Georgia's Doctor of Pharmacy program. Dr. Wade has numerous publications in academic and professional journals. Joseph T. DiPiro, PharmD is Executive Dean of the South Carolina College of Pharmacy, which is part of the University of South Carolina and the Medical University of South Carolina, USA. He received his bacheklor of science in pharmacy from the University of Connecticut and doctor of pharmacy from the University of Kentucky. He served a residency at the University of Kentucky Medical Center and a fellowship in clinical Immunology at Johns Hopkins University. Before coming to South Carolina, Dr. DiPiro was a faculty member at the University of Georgia College of Pharmacy and the Medical College of Georgia for 24 years. Robert A. Blouin, PharmD Jane M. Preumer, PharmD, BCOP, FASHP.show more

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