Preface. Part 1: Instrumentation Systems. Computer-Based Studies on Bioprocess Engineering: I-Tools for Process Analysis; S. Feyo de Azevedo, et al. Computer-Based Studies on Bioprocess Engineering: II-Tools for Process Operation; S. Feyo de Azevedo, et al. Multivariable Control of a Continuous Culture; P.A. Gostomski, et al. Steady States in Continuous Culture; H.R. Bungay. Introduction to Artificial Intelligence; H.R. Bungay. Nonlinear Oscillations in Bioreaction Systems; R.Y.K. Yang, J. Su. Bioreactor Instrumentation and Biosensors; K. Schugerl. Bioreactors for Improved Process Performance; K. Schugerl. Bioreactor Fault Detection Using Data Reconciliation; J.J. Prior and C.L. Cooney. The Design Approach of Multiproduct Plants; J. Mata-Alvarez, C. Rolz. Strategies for Bioreactor Scale-Up; F. Mavituna. Statistical Design and Analysis of Experiments; C.E. Rolz. Simulation of a Complex Biotechnological Process Using an Object-Oriented Knowledge-Based System; M. Polakovic, C.F. Mandenius. Part 2: Enzyme Technology. The Implication of Ph on the Design of an Enzymatic Reactor for Penicillin Hydrolysis; A. Gomez-Aguirre, et al. Simulation of Batch Enzyme Reactors; A. Lopez-Munguia. Modeling of Membrane Bioreactors; D.M.F. Prazeres, et al. Membrane Bioreactor with Immobilized Lipase: Modelling and Computational Considerations; F.X. Malcata. Protein Extraction by Reversed Micellar Systems; M.R. Aires-Barros, J.M.S. Cabral. Part 3: Environmental Biotechnology. Role of Cyanide on Polycyclic Aromatic Hydrocarbon Degradation in Manufactured Gas Plant Soils; L.S. Clesceri, et al. Biomass Refining; H.R. Bungay. Anaerobic Methane Fermentation in a Plug-Flow Reactor Treating OrganicWastes; J. Mata-Alvarez, P. Llabres-Luengo. Activated Sludge; H.R. Bungay. Biotechnology and the Environment; A. Moser. Part 4: Food Applications. An Efficient Computer Programme for the Simulation of Food Freezing Operations; A.M. Figueiredo, A.M. Sereno. Modelling and Simulation of Convective Green-Pea Drying; G.L. Medeiros, A.M. Sereno. Part 5: Metabolic Engineering. Modelling of the Baculovirus Infection Process in Insect Cell Reactor Configurations; C.D. De Gooijer, et al. Use of Fed-Batch Operation to Improve Secondary Metabolite Production; K.K. Wallace, et al. Bioreactor Design for Animal Cell Culture: With Special Reference to Mass Transfer; R.E. Spier. General Methodology in Bioprocess Engineering; A. Moser. Industrial Scale Antibiotic Production: Process Kinetic Analysis and Process Design; A. Moser. Oxygen Transfer and Microbial Growth; A. Moser. Classroom Adaptation of Escherichia Coli Single Cell Model; G.J. Stanlake, M.L. Shuler. Kinetics of Continuous Microbial Culture: Plug-Flow, Chemostat, Turbidostat and Fed-Batch Principles; E.J. VanDamme, M. Van Speybroeck. A Spreadsheet Simulation of a Differential Reactor for Estimating Kinetic Constants; J. Mata-Alvarez, P. Clapes. Production of Fuel Alcohols by Fermentation: Engineering and Physiological Basis for Improving Processes; G. Goma, et al. Index.