Computational Neuroanatomy
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Computational Neuroanatomy : Principles and Methods

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In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.show more

Product details

  • Hardback | 469 pages
  • 197.6 x 248.9 x 29.2mm | 1,220.17g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • 2002 ed.
  • XIII, 469 p.
  • 158829000X
  • 9781588290007

Review quote

"...a useful addition to major neuroscience libraries." -Neuroradiologyshow more

Back cover copy

Computer models, simulations, and visualization now offer unprecedented opportunities to obtain a deeper understanding of the complexity of nervous system structures. In Computational Neuroanatomy: Principles and Methods, the groundbreaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models. Their peer-reviewed articles describe the algorithms needed to generate virtual dendrites in 3D and explain the theory and practice of computing network connectivity. They also discuss the use of 3D graphics for the quantitative description of neural tissue from single neurons to regions, as well as the methods for integrating anatomy and physiology in neuronal models. Authoritative and groundbreaking, Computational Neuroanatomy: Principles and Methods comprehensively integrates for the first time both the principles and the methods that are playing a central role in generating a complete, unitary, and functional neuroanatomical model of the brain.show more

Table of contents

Part I Computing the Brain and the Computing Brain Giorgio A. Ascoli Part II Some Approaches to Quantitative Dendritic Morphology Robert E. Burke and William B. Marks Generation and Description of Neuronal Morphology Using L-Neuron: A Case Study Duncan E. Donohue, Ruggero Scorcioni, and Giorgio A. Ascoli Optimal-Wiring Models of Neuroanatomy Christopher Cherniak, Zekeria Mokhtarzda, and Uri Nodelman The Modeler's Workspace: Making Model-Based Studies of the Nervous System More Accessible Michael Hucka, Kavita Shankar, David Beeman, and James M. Bower The Relationship Between Neuronal Shape and Neuronal Activity Jeffrey L. Krichmar and Slawomir J. Nasuto Practical Aspects in Anatomically Accurate Simulations of Neuronal Electrophysiology Maciej T. Lazarewicz, Sybrand Boer-Iwema, and Giorgio A. Ascoli Part III Predicting Emergent Properties of Neuronal Ensembles Using a Database of Individual Neurons Gwen A. Jacobs and Colin S. Pittendrigh Computational Anatomical Analysis of the Basal Forebrain Corticopetal System Laszlo Zaborszky, Attila Csordas, Derek L. Buhl, Alvaro Duque, Jozsef Somogyi, and Zoltan Nadasdy Architecture of Sensory Map Transformations: Axonal Tracing in Combination with 3D Reconstruction, Geometric Modeling, and Quantitative Analyses Trygve B. Leergaard and Jan G. Bjaalie Competition in Neuronal Morphogenesis and the Development of Nerve Connections Arjen van Ooyen and Jaap van Pelt Axonal Navigation Through Voxel Substrates: A Strategy for Reconstructing Brain Circuitry Stephen L. Senft Principle and Applications of Diffusion Tensor Imaging: A New MRI Technique for Neuroanatomical Studies Susumu Mori Part IV Computational Methods for the Analysis of Brain Connectivity Claus C. Hilgetag, Rolf Kotter, Klaas E. Stephan, and Olaf Sporns Development of Columnar Structures in Visual Cortex Miguel A. Carreira-Perpinan and Geoffrey J. Goodhill Multi-level Neuron and Network Modeling in Computational Neuroanatomy Rolf Kotter, Pernille Nielse, Jonas Dyhrfjeld-Johnsen, Friedricj T. Sommer, and Georg Northoff Quantitative Neurotoxicity David S. Lester, Joseph P. Hanig, and P. Scott Pine How the Brain Develops and How it Functions: Application of Neuroanatomical Data of the Developing Human Cerebral Cortex to Computational Models William Rodman Shankle, Junko Hara, James Fallon, and Benjamin H. Landing Towards Virtual Brains Alexei Samsonovich and Giorgio A. Ascolishow more

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