The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins

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The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition, provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the first edition (published in 1991), with 70 per cent totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field.
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Product details

  • Hardback | 650 pages
  • 217.7 x 285.2 x 42.7mm | 2,448.42g
  • Academic Press Inc
  • San Diego, United States
  • Revised
  • 2nd Revised edition
  • colour illustrations
  • 0120530759
  • 9780120530755

Table of contents

J.E. Alouf and J.H. Freer, Preface. U. Dobrindt and J. Hacker, Plasmids, Phages, and Pathogenicity Islands: Lesson on the Evolution of Bacterial Toxins. Toxins Acting on Cytosolic Targets: P. Bouquet, The RAS Superfamily of Small GTP-Binding Proteins as Targets for Bacterial Toxins. S. Olsnes, J. Wesche, and P.Ø. Falnes, Binding, Uptake, Routing, and Translocation of Toxins with Intracellular Sites of Action. R.K. Holmes and J.G. Siekierke, Regulation of Diptheria Toxin Production. T. Hirst, Cholera Toxin and E. Coli Heat-Labile Enterotoxins. C. Locht and R. Antoine, Bordetella Pertussis Protein Toxins. M. Thelestam, E. Chavez-Olarte, M. Moos, and C. von Eichel Streiber, Clostridial Toxins Acting on the Cytoskeleton. M.R. Popoff and J.-C. Marvaud, Structural and Genomic Features of Clostridial Neurotoxins. J. Herreros, G. Lalli, C. Montecucco, and G. Schiavo, Pathophysiological Properties of Clostridial Neurotoxins. D.W.K. Acheson and G.T. Keusch, The Family of Shiga Toxins. S.A. Leppla, The Bifactorial Bacillus Anthracis Lethal and Oedema Toxins. C. Montecucco, E. Papini, M. de Bernard, J.R. Telford, and R. Rappuoli, Helicobacter Pylori Vacuolating Cytotoxin and Associated Pathogenic Factors. Membrane-Damaging Toxins: G. Menestrina and B.V. SemjĊn, Biophysical Methods and Membrane Models for the Study of Bacterial Pore Forming Cytolysins. R.W. Titball, Membrane Damaging and Cytotoxic Phospholipases. A. Ludwig and W. Goebel, The Family of the Multigenic Encoded RTX Toxins. V. Braun and R. Hertle, The Family of Serratia and Proteus Cytolsins. J.T. Buckley, The Channel-Forming Toxin Aerolysin. S. Shindoa, Vibrio Cholerae and Other Vibrio Species Haemolysins. J. Dufourcq, S. Castano, and J.-C. Talbot, Toxin, d-Related Hemolytic Toxins and Peptide Analogues. G. Prévost, Staphylococcal Bi-Component Leucotoxins. M.S. Gilmore, M. Callegan, and B. Jett, Multicomponent Cytolysins of Enterococcus Faecalis and Bacillus Cereus. R.K. Tweten and B.R. Sellman, Clostridium Septicum Pore-Forming and Lethal a-Toxin. J.E. Alouf, The Family of the Cholesterol-Binding Cytolysins. J.E. Alouf and M. Palmer, Streptolysin O (SLO). T.J. Mitchell, Pneumolysin: Structure, Function, and Role in Disease. J. Rossjohn, R.K. Tweten, J.I. Rood, and M. Parker, Perfringolysin O. T. Jacobs, A. Darji, S. Weiss, and T. Chakraborty, Listeriolysin, the Thiol-Activated Hemolysin of Listeria Monocytogenes. Other Toxins of Clinical, Pharmacologic, and Therapeutic Interest: J.D. Dubreuil, Enterotoxigenic Escherichia Coli Heat-Stable Toxins. T. Takeda, K.-I. Yoshino, T. Ramamurthy, and G.B. Nair, Heat-Stable Enterotoxins of Vibrio and Yersinia Species. C.L. Sears, Bacteroides Fragilis Toxins. J.E. Alouf, H. Müller-Alouf, and W. Köhler, Superantigenic Streptococcus Pyogenes Erythrogenic/Pyrogenic Exotoxins and Other Mitogens. S.R. Monday and G.A. Bohach, Properties of Staphylococcus Aureus Enterotoxins and Toxic Shock Syndrome Toxin-1. C. Carnoy and M. Simonet, Yersinia Pseudotuberculosis Superantigenic Toxins. D.L. Stevens and A.E. Bryant, The Pathogenesis of Shock and Tissue Injury in Clostridia Gas Gangrene. B. König, A. Drynda, A. Ambrosch, and W. König, Toxin-Induced Modulation of Inflammatory Processes. Y. Piímont, Staphylococcal Epidermolytic Toxins. P.E. Granum and S. Brynestad, Bacterial Toxins as Food Poisons. J.C. VanderSpek and J.R. Murphy, Diphtheria Toxins-Based Interleukin 2 Fusion Proteins. A.-M. Svennerholm and J. Holmgren, Toxin-Based Vaccines for Cholera and Escherichia Coli Diarrheas.
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Review quote

"Anyone interested in bacterial protein toxins will easily find here all the relevant information or references required. essential contribution , the keystone in the field. -TRENDS IN BIOCHEMICAL SCIENCES (November 2000) ...considerably more comprehensive and explicit than the first edition...well-written, up-to-date, thorough, and detailed information with substantive reference excellent and valuable reference book that is a must for any microbiology library. -Brenda Anne Wilson, University of Illinois, in ASM NEWS (2000) This second edition is a remarkably clear and thoughtful resource on the genetics, stucture, function, and mechanism of action of microbial protein toxins. ...I consider this book to be an exceptional academic effort and would highly recommend to anyone working in this field that they acquire the text for their personal collection. Furthermore, I suggest that it would be an outstanding textbook for a graduate level course on molecular pathogenesis or microbial toxicology. I find it to be first-rate. -Charles E. Edmiston, Jr., PhD, Medical College of Wisconsin, for DOODY'S ...the publication of the second edition of The Comprehensive Sourcebook of Bacterial Protein Toxins is particularly welcome. This new version is not just an update of the previous volume; rather, it is an entirely new book, which describes novel concepts such as pathogenicity islands, as well as novel toxins. This book contains contributions from authoritative toxin experts and comprehensive references on the subject. Furthermore, it gives a good perspective of the field, providing clear indications on the future directions and targets in bacterial-protein-toxin research. What emerges is the tendency to overlap and mix the expertise of microbiology, cell biology and molecular medicine, which provides insights and synergies unmatched before, allowing a more effective exploration of the richness of the bacterial world. -Giampietro Schiavo, Giovanna Lalli and Judit Herreros, Molecular Neuropathology Laboratory, Imperial Cancer Research Fund, London, UK for TRENDS IN MICROBIOLOGY Praise for the First Edition ...Recommended without reservation... first-class collection of up-to-date, detailed, well presented articles... an essential text... covers every aspect of bacterial protein toxins... -SOCIETY FOR GENERAL MICROBIOLOGY QUARTERLY ...a well-balanced, comprehensive text offering a wealth of knowledge on bacterial toxins... -AMERICAN SOCIETY FOR MICROBIOLOGY NEWS ...a good source on specific topics of interest. -SCIENCE ...a most complete and exhaustive referenced up-to-date textbook and reference book on bacterial protein toxins... the chapters are clearly written by internationally known specialists and are well documented. -LWT FOOD SCIENCE AND TECHNOLOGY
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About J. E. Alouf

Joseph E. Alouf is Professor of Microbiology at the Pasteur Institute of Lille. He is former Head of the Department of Bacteriology and Mycology at the Pasteur Institute at Paris and Chairman of its Scientific Council. He served as Secretary General of the French Society of Immunology from 1984-1986 and President of the Federation of the European Microbiological Societies from 1989-1992. His 40-year research work relates to the field of bacterial protein toxins and immunology of infectious diseases. He is also the co-editor of several books.
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